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紫外线B光疗法治疗银屑病:探寻最佳方案。

Ultraviolet B radiation therapy for psoriasis: Pursuing the optimal regime.

作者信息

Matos Tiago R, Ling Tsui C, Sheth Vaneeta

机构信息

Newton Wellesley Hospital Department of Dermatology, Newton, MA; Academic Medical Center, Department of Dermatology, University of Amsterdam, Amsterdam, 1105 AZ, Netherlands.

Consultant Dermatologist for Phototherapy and Photobiology Unit, Dermatology Centre, Salford Royal Hospital, Manchester, M6 8 HD, UK.

出版信息

Clin Dermatol. 2016 Sep-Oct;34(5):587-93. doi: 10.1016/j.clindermatol.2016.05.008. Epub 2016 May 20.

DOI:10.1016/j.clindermatol.2016.05.008
PMID:27638437
Abstract

Psoriasis is a chronic and common disease mediated by resident memory T cells that negatively affects a broad range of people worldwide. One of the oldest and most commonly used treatments is phototherapy. We reviewed the existing literature on the four main ultraviolet B (UVB) modalities of phototherapy in the management of psoriasis: heliotherapy, broadband UVB, narrowband UVB, and excimer laser and lamp. Despite the many studies done on these therapies, there is significant variation in their prescription and use. Phototherapy remains one of the most effective and safest treatments for psoriasis. We provide an updated comprehensive overview of UVB phototherapy for psoriasis to help physicians optimize their choice of modality and dosing regimen to ensure optimal outcomes for psoriasis patients. © 2016 Elsevier Inc. All rights reserved.

摘要

银屑病是一种由驻留记忆T细胞介导的慢性常见疾病,对全球众多人群产生负面影响。最古老且最常用的治疗方法之一是光疗。我们回顾了现有关于光疗的四种主要紫外线B(UVB)模式用于银屑病治疗的文献:日光疗法、宽带UVB、窄带UVB以及准分子激光和准分子灯。尽管对这些疗法进行了大量研究,但它们的处方和使用仍存在显著差异。光疗仍然是治疗银屑病最有效且最安全的方法之一。我们提供了一份关于UVB光疗治疗银屑病的最新综合概述,以帮助医生优化其模式选择和给药方案,确保为银屑病患者带来最佳疗效。© 2016爱思唯尔公司。保留所有权利。

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Ultraviolet B radiation therapy for psoriasis: Pursuing the optimal regime.紫外线B光疗法治疗银屑病:探寻最佳方案。
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引用本文的文献

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NOD2 expression in psoriasis before and after treatment with Narrowband Ultraviolet B phototherapy.窄谱中波紫外线光疗前后银屑病中NOD2的表达
Arch Dermatol Res. 2025 Jan 16;317(1):260. doi: 10.1007/s00403-024-03690-x.
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High-Throughput RNA Sequencing Reveals the Effect of NB-UVB Phototherapy on Major Inflammatory Molecules of Lesional Psoriasis.高通量RNA测序揭示窄谱中波紫外线光疗对银屑病皮损主要炎症分子的影响。
Psoriasis (Auckl). 2021 Nov 26;11:133-149. doi: 10.2147/PTT.S335913. eCollection 2021.
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/Cdx-2 AA Variant of Defines the Response to Phototherapy amongst Patients with Psoriasis.
Cdx-2的AA变体决定了银屑病患者对光疗的反应。
Life (Basel). 2021 Jun 16;11(6):567. doi: 10.3390/life11060567.
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Ultraviolet B Inhibits IL-17A/TNF-α-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts.紫外线B通过降低成纤维细胞上IL-17RA和IL-17RC的表达来抑制IL-17A/TNF-α刺激的人皮肤成纤维细胞活化。
Front Immunol. 2017 Feb 3;8:91. doi: 10.3389/fimmu.2017.00091. eCollection 2017.