Esmat Samia, Mostafa Wedad, Hegazy Rehab A, Shalaby Suzan, Sheth Vaneeta, Youssef Randa, El-Mofty Medhat
Phototherapy Unit, Dermatology Department, Faculty of Medicine, Cairo University, Egypt.
Phototherapy Unit, Dermatology Department, Faculty of Medicine, Cairo University, Egypt.
Clin Dermatol. 2016 Sep-Oct;34(5):594-602. doi: 10.1016/j.clindermatol.2016.05.009. Epub 2016 May 20.
Phototherapy has been the mainstay of vitiligo therapy for several decades. A variety of wavelengths and modalities are available, but narrowband ultraviolet B remains the safest and most commonly used treatment. Acting on multiple steps in vitiligo pathogenesis, narrowband ultraviolet B is one of the few therapies that can effectively induce stabilization and stimulate repigmentation. Achievement of optimal results involves using a combination of appropriate treatment protocols, careful patient selection, and patient education to set expectations. Individual patient characteristics, including disease activity, vitiligo phenotype, lesion location, and skin phototype, should all be considered, along with combination therapies.
几十年来，光疗一直是白癜风治疗的主要方法。有多种波长和治疗方式可供选择，但窄谱中波紫外线仍然是最安全、最常用的治疗方法。窄谱中波紫外线作用于白癜风发病机制的多个环节，是少数能够有效诱导病情稳定并刺激色素再生的治疗方法之一。要取得最佳效果，需要结合适当的治疗方案、仔细挑选患者以及对患者进行教育以设定合理预期。应综合考虑个体患者的特征，包括疾病活动度、白癜风表型、皮损部位和皮肤光类型，同时也要考虑联合治疗方法。
