Folléa G
Établissement français du sang (EFS), 20, avenue du Stade-de-France, 93218 La-Plaine-Saint-Denis, France.
Transfus Clin Biol. 2016 Nov;23(4):175-184. doi: 10.1016/j.tracli.2016.08.008. Epub 2016 Sep 14.
In a context of regular review of transfusion practice, the aim of this review is to present an update of the scientific basis of the so-called "patient blood management" (PBM), the state of its development in Europe, and possible ways to progress its development further in France.
Analysis and synthesis of the data from scientific literature on the scientific basis of PBM (methods, indications, efficacy, risks, efficiency).
PBM appears as an evidence-based, patient centred, multidisciplinary approach, aiming to optimise the care of patients who might need transfusion and, consequently, the use of blood products. PBM is based on three pillars: optimise the patient's own blood supplies, minimise blood loss, optimise patient's tolerance of anaemia. Available scientific evidence can be considered as sufficient to consider PBM guidelines and practices as an indispensable complement to the transfusion medicine guidelines and practices. Several countries have launched PBM programmes (alternatives to allogeneic transfusion and optimisation of the use of blood components). Although current French national transfusion guidelines contain some PBM measures, PBM programmes should be further developed in France, primarily for medical reasons.
Possible ways, using the existing basis having proved to be effective, are proposed to further develop PBM in France, as a complement to transfusion medicine, with the participation of involved stakeholders, including experts from relevant medical specialties, both at local and national levels.
在定期回顾输血实践的背景下,本综述旨在介绍所谓“患者血液管理”(PBM)的科学基础的最新情况、其在欧洲的发展状况,以及在法国进一步推动其发展的可能途径。
对关于PBM科学基础(方法、适应症、疗效、风险、效率)的科学文献数据进行分析和综合。
PBM表现为一种基于证据、以患者为中心的多学科方法,旨在优化可能需要输血的患者的护理,从而优化血液制品的使用。PBM基于三大支柱:优化患者自身的血液供应、尽量减少失血、优化患者对贫血的耐受性。现有科学证据足以将PBM指南和实践视为输血医学指南和实践不可或缺的补充。几个国家已经启动了PBM项目(异体输血的替代方法和血液成分使用的优化)。尽管目前法国国家输血指南包含一些PBM措施,但PBM项目在法国应进一步发展,主要是出于医学原因。
提出了利用已被证明有效的现有基础在法国进一步发展PBM的可能途径,作为输血医学的补充,由包括相关医学专业专家在内的利益相关者在地方和国家层面参与。