Byard P J, Mukherjee B N, Bhattacharya S K, Russell J M, Rao D C
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106.
Am J Phys Anthropol. 1989 Jul;79(3):305-11. doi: 10.1002/ajpa.1330790306.
Fifty-three households in a small Indian fishing community were surveyed for blood pressure, pulse rate, and anthropometric measurements (height, weight, and three skinfolds). In addition to nuclear family relationships, correlations for extended family members and in-laws living within a common household were estimated by maximum likelihood. Based on likelihood ratio tests, the hypothesis that correlations among genetically unrelated pairs from the same household are zero is rejected for systolic blood pressure. Among genetically related individuals, the degree of relationship does not affect the magnitude of the blood pressure correlations. For the anthropometric measurements, family resemblance is significant only for first-degree relatives, except that the correlation for uncle-child pairs is significant for subscapular skinfold, and brother-in-law-sister-in-law pairs resemble each other for height and weight. The results suggest that common household environment is a significant determinant of blood pressure but not fatness in this population.
在印度一个小型渔业社区，对53户家庭进行了血压、脉搏率以及人体测量（身高、体重和三处皮褶厚度）方面的调查。除了核心家庭成员关系外，还通过最大似然法估计了居住在同一家庭中的大家庭成员和姻亲之间的相关性。基于似然比检验，同一家庭中基因不相关对之间相关性为零的假设在收缩压方面被拒绝。在基因相关个体中，亲属关系程度并不影响血压相关性的大小。对于人体测量，家族相似性仅在一级亲属中显著，不过叔侄对的肩胛下皮褶厚度相关性显著，姐夫与嫂子在身高和体重方面彼此相似。结果表明，在这个群体中，共同的家庭环境是血压的一个重要决定因素，但不是肥胖的重要决定因素。
