Guru Nanak Dev University, Amritsar, Punjab, India.
Asia Pac J Public Health. 2012 Jan;24(1):104-16. doi: 10.1177/1010539510372539. Epub 2010 Jun 21.
Familial aggregation of blood pressure with respect to anthropometric characteristics was investigated among the Lobana (a tribal origin) population in Punjab, a North Indian state. A total of 505 individuals comprised the study sample, constituting 116 families of 3 generations. The study represents a multivariate model analysis, which includes family data with respect to blood pressure phenotypes and other metric measurements such as height, weight, body mass index, waist and hip circumferences, waist-to-hip ratio (WHR), and 4 skinfold measurements. A higher correlation for almost all sets of anthropometric variables with blood pressure was found among the offspring generation as compared with the parental and grandparental generations. The study confirmed that the familial aggregation of blood pressure with respect to anthropometric measurements is strong in the offspring generation. The findings suggest that sharing a household environment has a significant effect on familial aggregation especially for systolic blood pressure.
本研究旨在调查印度旁遮普邦的洛巴纳（部落起源）人群中，血压与人体测量特征的家族聚集情况。共有 505 人组成了研究样本，包括 116 个三代同堂的家庭。该研究采用了多变量模型分析，其中包括与血压表型以及身高、体重、体重指数、腰围和臀围、腰臀比（WHR）和 4 个皮褶厚度等身体测量相关的家族数据。与父辈和祖辈相比，子代人群中几乎所有人体测量变量与血压之间的相关性更高。本研究证实，子代人群中血压与人体测量指标的家族聚集性较强。研究结果表明，共享家庭环境对家族聚集尤其是收缩压有重要影响。
