Suppr超能文献

高血压治疗与跌倒担忧:收缩压干预试验的基线数据

Hypertension Treatment and Concern About Falling: Baseline Data from the Systolic Blood Pressure Intervention Trial.

作者信息

Berlowitz Dan R, Breaux-Shropshire Tonya, Foy Capri G, Gren Lisa H, Kazis Lewis, Lerner Alan J, Newman Jill C, Powell James R, Riley William T, Rosman Robert, Wadley Virginia G, Williams Julie A

机构信息

Bedford Veterans Affairs Hospital, Bedford, Massachusetts.

Department of Health Law, Policy and Management, School of Public Health, Boston University, Boston, Massachusetts.

出版信息

J Am Geriatr Soc. 2016 Nov;64(11):2302-2306. doi: 10.1111/jgs.14441. Epub 2016 Sep 19.

Abstract

OBJECTIVES

To determine the extent of concern about falling in older adults with hypertension, whether lower blood pressure (BP) and greater use of antihypertensive medications are associated with greater concern about falling, and whether lower BP has a greater effect on concern about falling in older and more functionally impaired individuals.

DESIGN

Secondary analysis involving cross-sectional study of baseline characteristics of participants enrolled in the Systolic Blood Pressure Intervention Trial (SPRINT).

SETTING

Approximately 100 outpatient sites.

PARTICIPANTS

SPRINT enrollees aged 50 and older (mean age 69) diagnosed with hypertension (N = 2,299).

MEASUREMENTS

Concern about falling was determined using the shortened version of the Falls Efficacy Scale International as measured at the baseline examination.

RESULTS

Mild concern about falling was present in 29.3% of participants and moderate to severe concern in 17.9%. Neither low BP (systolic BP<120 mmHg, diastolic BP <70 mmHg) nor orthostatic hypotension was associated with concern about falling (P > .10). Participants with moderate to severe concern about falling were taking significantly more antihypertensive medications than those with mild or no concern. After adjusting for baseline characteristics, no associations were evident between BP, medications, and concern about falling. Results were similar in older and younger participants; interactions between BP and age and functional status were not significantly associated with concern about falling.

CONCLUSION

Although concern about falling is common in older adults with hypertension, it was not found to be associated with low BP or use of more antihypertensive medications in baseline data from SPRINT.

摘要

目的

确定老年高血压患者对跌倒的担忧程度,较低的血压(BP)和更多地使用抗高血压药物是否与对跌倒的更大担忧相关,以及较低的血压对老年和功能障碍更严重的个体的跌倒担忧是否有更大影响。

设计

对收缩压干预试验(SPRINT)参与者的基线特征进行横断面研究的二次分析。

设置

约100个门诊地点。

参与者

SPRINT研究中年龄在50岁及以上(平均年龄69岁)且被诊断为高血压的参与者(N = 2299)。

测量

在基线检查时使用国际跌倒效能量表的简化版来确定对跌倒的担忧程度。

结果

29.3%的参与者存在对跌倒的轻度担忧,17.9%存在中度至重度担忧。低血压(收缩压<120 mmHg,舒张压<70 mmHg)和直立性低血压均与对跌倒的担忧无关(P>0.10)。对跌倒有中度至重度担忧的参与者服用的抗高血压药物明显多于轻度担忧或无担忧的参与者。在调整基线特征后,血压、药物与对跌倒的担忧之间无明显关联。老年和年轻参与者的结果相似;血压与年龄和功能状态之间的相互作用与对跌倒的担忧无显著关联。

结论

尽管老年高血压患者对跌倒的担忧很常见,但在SPRINT的基线数据中未发现其与低血压或更多使用抗高血压药物有关。

相似文献

引用本文的文献

本文引用的文献

3
Hypertension treatment and falls: should we be concerned?高血压治疗与跌倒:我们应该关注吗?
J Gen Intern Med. 2014 Dec;29(12):1577-8. doi: 10.1007/s11606-014-3016-5.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验