Adamowicz Krzysztof, Zaucha Renata
Regional Hospital in Wejherowo, Jagalskiego Street 10, 84-200, Wejherowo, Pomerania, Poland.
Depatment of Oncology and Radiotherapy, Medical University of Gdansk, 7 Debinki St., 80-211, Gdansk,, Poland.
J Cancer Educ. 2018 Apr;33(2):309-316. doi: 10.1007/s13187-016-1112-4.
Colorectal cancer is the second most common cause of cancer deaths worldwide. Although progress in the development of new drugs over the last two decades has expanded treatment options for this disease, many significant problems relating to their optimization remain to be solved. Data on the cancer knowledge and the healthy behavior and lifestyle in patients with colorectal cancer in Poland is missing. We analyzed the course and results of treatment of first-line chemotherapy in 165 patients diagnosed with colorectal cancer treated between May 2010 and December 2013. The respondent's knowledge in the field of cancer and their lifestyle before and after the treatment were rated. The results were compared with a control group. Mean age was 60.89 ± 8.69 years, median 59 years. The general knowledge about cancer and the level of healthy lifestyle before treatment were low. After treatment, both the knowledge about cancer and the level of healthy lifestyle increased compared to the control group. There was a clear relationship between the level of knowledge about cancer and the willingness to adopt attitudes and healthy behavior by patients. In our analysis, the overall quality of life in patients treated with first-line palliative chemotherapy of colorectal cancer did not change during treatment. Our results indicate the need to implement an educational program on cancer prevention in treated patients, and the analysis of quality of life and other factors than treatment effect remains controversial.
结直肠癌是全球第二大常见癌症死因。尽管过去二十年来新药研发取得了进展，扩大了这种疾病的治疗选择，但在优化治疗方面仍有许多重大问题有待解决。波兰缺乏关于结直肠癌患者的癌症知识以及健康行为和生活方式的数据。我们分析了2010年5月至2013年12月期间确诊为结直肠癌的165例患者一线化疗的治疗过程和结果。对受访者在治疗前后的癌症领域知识及其生活方式进行了评分。将结果与对照组进行比较。平均年龄为60.89±8.69岁，中位数为59岁。治疗前患者对癌症的一般知识和健康生活方式水平较低。与对照组相比，治疗后患者对癌症的知识和健康生活方式水平均有所提高。患者对癌症的知识水平与采取态度和健康行为的意愿之间存在明显关系。在我们的分析中，接受结直肠癌一线姑息化疗的患者的总体生活质量在治疗期间没有变化。我们的结果表明，需要对接受治疗的患者实施癌症预防教育计划，并且对生活质量和治疗效果以外的其他因素进行分析仍存在争议。
