Eamchan P, Nisalak A, Foy H M, Chareonsook O A
Ministry of Public Health, Banghok, Thailand.
Am J Trop Med Hyg. 1989 Jul;41(1):95-101.
A severe epidemic of dengue hemorrhagic fever (DHF) in Nakhon Ratchasima, Thailand in August of 1987 prompted a field investigation. DHF rates of 0.4-6.5 cases per 1,000 residents in subdistricts and 2-15 cases per 1,000 residents in 10 villages investigated were reported. Epidemics peaked in neighboring villages at different times; in June and July, and in August before the rainy season began late in the month. In 4 primary schools representing 6 villages, sera from groups of randomly selected children were tested for dengue IgM with the antibody capture ELISA test. Rates of recent dengue infection were 10-65% in the schools and correlated closely with reported rates of DHF. In an effort to control vectors, malathion fog and temephos (1% abate sand granules) were applied. Villagers were educated in prevention and were urged to cover water receptacles. The percentage of houses with larvae dropped from 67 to 20, the percentage of containers with larvae decreased from 30 to 5, and the number of containers with larvae per 100 households decreased from 221 to 33. This was a serious epidemic in which conventional control measures were only moderately effective.
1987年8月，泰国呵叻府爆发了严重的登革出血热（DHF）疫情，促使相关部门展开了实地调查。据报告，在所调查的各个分区中，登革出血热发病率为每1000名居民中有0.4 - 6.5例，在10个村庄中，发病率为每1000名居民中有2 - 15例。疫情在邻近村庄于不同时间达到高峰，分别在6月和7月，以及8月雨季在该月下旬开始之前。在代表6个村庄的4所小学中，对随机抽取的儿童群体血清进行了登革热IgM抗体捕捉ELISA检测。学校近期登革热感染率为10% - 65%，与报告的登革出血热发病率密切相关。为了控制病媒，使用了马拉硫磷烟雾剂和双硫磷（1%杀螟松砂粒剂）。对村民进行了预防教育，并敦促他们遮盖储水容器。有幼虫的房屋比例从67%降至20%，有幼虫的容器比例从30%降至5%，每100户家庭中有幼虫的容器数量从221个降至33个。这是一场严重的疫情，传统控制措施仅取得了一定程度的成效。
