Hawkins E C, DeNicola D B
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
Am J Vet Res. 1989 Jun;50(6):855-9.
Bronchoalveolar lavage fluid was collected from 12 anesthetized cats by use of an endotracheal tube and syringe adapter. The safety of the technique was evaluated by monitoring mucous membrane color, capillary refill time, pulse rate, respiratory rate, ECG, and arterial blood gas tensions and by necropsy findings. Group A consisted of 3 cats that were administered (by lavage) 4 aliquots of 20 ml of saline solution during anesthesia for placement of femoral artery catheters. Group B consisted of 4 cats that were administered a smaller total volume of saline solution (3 aliquots of 5 ml/kg of body weight) during a separate anesthetic period, other than the one for placement of catheters. Group C consisted of 5 cats administered 3 aliquots (5 ml/kg) of saline solution during a separate anesthetic period and administered supplemental oxygen for 5 to 10 minutes before and for 20 minutes after the lavage procedure. Group-A cats had a prolonged recovery period that was attributed to the lengthy anesthetic period required for placement of femoral catheters. The effect was eliminated in the cats of the other groups in which the lavage procedure itself accounted for only 5 to 10 minutes of anesthetic time. Evaluation of mucous membrane color, capillary refill time, ECG, pulse, and respiratory rate revealed no persistent abnormalities. Transient increase in pulse and respiratory rate was seen in some cats. Blood gas analysis revealed noticeable decrease in arterial oxygen pressures (Pao2) after the lavage procedure. In group-C cats, oxygen supplementation allowed the maintenance of normal or above normal Pao2.(ABSTRACT TRUNCATED AT 250 WORDS)
通过气管内插管和注射器接头从12只麻醉猫中采集支气管肺泡灌洗液。通过监测粘膜颜色、毛细血管再充盈时间、脉搏率、呼吸频率、心电图、动脉血气张力以及尸检结果来评估该技术的安全性。A组由3只猫组成,在麻醉期间(通过灌洗)给予4份20毫升的盐溶液,用于放置股动脉导管。B组由4只猫组成,在放置导管的麻醉期之外的另一个麻醉期内给予总量较少的盐溶液(3份,5毫升/千克体重)。C组由5只猫组成,在另一个麻醉期内给予3份(5毫升/千克)盐溶液,并在灌洗程序前5至10分钟和后20分钟给予补充氧气。A组猫的恢复期延长,这归因于放置股动脉导管所需的较长麻醉期。在其他组的猫中这种影响被消除,在这些组中灌洗程序本身仅占麻醉时间的5至10分钟。对粘膜颜色、毛细血管再充盈时间心电图、脉搏和呼吸频率的评估未发现持续异常。一些猫出现了脉搏和呼吸频率的短暂增加。血气分析显示灌洗程序后动脉血氧分压(Pao2)明显下降。在C组猫中,补充氧气使Pao2维持在正常或高于正常水平。(摘要截短至250字)