Yoshihara T, Nomoto M, Hayasaki K, Kanda T, Konno A, Kaneko T
Department of Otolaryngology, Matsudo City Hospital, Chiba, Japan.
Auris Nasus Larynx. 1989;16(1):43-50. doi: 10.1016/s0385-8146(89)80007-0.
Primary squamous cell carcinoma of the parotid gland is a rare tumor. Histological and ultrastructural features of a primary squamous cell carcinoma arising in the right parotid gland is presented. Light microscopically the tumor consisted of poorly differentiated squamous cell nests. PAS reaction was negative. Ultrastructurally the tumor cells were oval or spindle shaped and the cytoplasmic processes were frequently found. The majority of the tumor cells contained numerous intermediate filaments in their cytoplasm. No secretory granule was found. The desmosomes were well developed. It is known that mucoepidermoid carcinoma may be often misdiagnosed as squamous cell carcinoma. These findings can enable us to distinguish primary squamous cell carcinoma from mucoepidermoid carcinoma of the parotid gland.
腮腺原发性鳞状细胞癌是一种罕见的肿瘤。本文呈现了一例发生于右侧腮腺的原发性鳞状细胞癌的组织学和超微结构特征。光镜下，肿瘤由低分化的鳞状细胞巢组成。PAS反应为阴性。超微结构上，肿瘤细胞呈椭圆形或梭形，且经常可见胞质突起。大多数肿瘤细胞的胞质内含有大量中间丝。未发现分泌颗粒。桥粒发育良好。众所周知，黏液表皮样癌常可能被误诊为鳞状细胞癌。这些发现有助于我们将腮腺原发性鳞状细胞癌与黏液表皮样癌区分开来。
