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三维放射治疗计划

Three-dimensional radiation treatment planning.

作者信息

Mohan R

出版信息

Australas Phys Eng Sci Med. 1989 Jun;12(2):73-91.

PMID:2764798
Abstract

A major aim of radiation therapy is to deliver sufficient dose to the tumour volume to kill the cancer cells while sparing the nearby healthy organs to prevent complications. With the introduction of devices such as CT and MR scanners, radiation therapy treatment planners have access to full three-dimensional anatomical information to define, simulate, and evaluate treatments. There are a limited number of prototype software systems that allow 3D treatment planning currently in use. In addition, there are more advanced tools under development or still in the planning stages. They require sophisticated graphics and computation equipment, complex physical and mathematical algorithms, and new radiation treatment machines that deliver dose very precisely under computer control. Components of these systems include programs for the identification and delineation of the anatomy and tumour, the definition of radiation beams, the calculation of dose distribution patterns, the display of dose on 2D images and as three dimensional surfaces, and the generation of computer images to verify proper patient positioning in treatment. Some of these functions can be performed more quickly and accurately if artificial intelligence or expert systems techniques are employed.

摘要

放射治疗的一个主要目标是向肿瘤体积输送足够剂量以杀死癌细胞,同时保护附近的健康器官以预防并发症。随着CT和MR扫描仪等设备的引入,放射治疗治疗计划制定者可以获取完整的三维解剖信息来定义、模拟和评估治疗方案。目前正在使用的允许进行三维治疗计划的原型软件系统数量有限。此外,还有更多先进工具正在开发中或仍处于规划阶段。它们需要复杂的图形和计算设备、复杂的物理和数学算法,以及能够在计算机控制下非常精确地输送剂量的新型放射治疗机器。这些系统的组成部分包括用于识别和描绘解剖结构及肿瘤的程序、辐射束的定义、剂量分布模式的计算、在二维图像上以及作为三维表面显示剂量,以及生成计算机图像以验证患者在治疗中的正确定位。如果采用人工智能或专家系统技术,其中一些功能可以更快、更准确地执行。

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