Mohan R, Brewster L J, Barest G D, Chui C S
Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Comput Methods Programs Biomed. 1989 Mar;28(3):157-70. doi: 10.1016/0169-2607(89)90145-4.
The objective of radiation therapy treatment is to eradicate a cancerous tumor while keeping the damage to nearby healthy organs to a minimum. A variety of tools employing computer graphics exist to aid in the planning and verification of treatments. Three-dimensional (3D) image information available from sources such as computerized tomography (CT) scanners is used to define the sizes, shapes, and spatial locations of the tumor and normal structures in the form of transverse contours. These object definitions are displayed in 3D perspective to enable the determination of the best possible directions from which to aim radiation beams at the tumor. The beams may be shaped to match the outline of the tumor, and their intensities may be modified using compensating devices. The results of calculations done to predict the distribution of radiation dose throughout the body due to a given set-up of beams can be displayed to the user in many ways. Dose may be shown in the form of isodose contours overlaid on transverse CT images, or on reconstructed image planes of arbitrary orientation in space. There are also a number of methods of 3D display; dose can be shown on the surface of objects, or in the form of isodose surfaces relative to anatomical structures. Computer-generated beam film images may be used to verify patient set-up and tumor coverage.
放射治疗的目标是根除癌性肿瘤,同时将对附近健康器官的损害降至最低。现有的各种利用计算机图形学的工具可辅助治疗计划的制定和验证。来自计算机断层扫描(CT)扫描仪等来源的三维(3D)图像信息用于以横向轮廓的形式定义肿瘤和正常结构的大小、形状和空间位置。这些物体定义以3D视角显示,以便确定将辐射束对准肿瘤的最佳可能方向。辐射束的形状可以调整以匹配肿瘤的轮廓,并且可以使用补偿装置来改变其强度。对于由于给定的束设置而预测的全身辐射剂量分布所进行的计算结果,可以通过多种方式显示给用户。剂量可以以等剂量线轮廓的形式叠加在横向CT图像上,或者在空间中任意方向的重建图像平面上显示。还有许多3D显示方法;剂量可以显示在物体表面,或者以相对于解剖结构的等剂量面的形式显示。计算机生成的束胶片图像可用于验证患者的摆位和肿瘤覆盖情况。