使用经颅多普勒超声检查法评估伊朗急性缺血性脑卒中患者颅内动脉狭窄的患病率。
Prevalence of intracranial artery stenosis in Iranian patients with acute ischemic stroke using transcranial Doppler ultrasonography.
作者信息
Shariat Abdolhamid, Niknam Leila, Izadi Sadegh, Salehi Alireza
机构信息
Shiraz Neuroscience Research Center, Clinical Neurology Research Center, Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.
Clinical Neurology Research Center, Department of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Iran J Neurol. 2016 Jul 6;15(3):133-9.
BACKGROUND
The aim of this study is to determine the frequency of intracranial artery stenosis in patients with acute ischemic stroke in Iran.
METHODS
A total of 169 patients with acute ischemic stroke were eligible to participate and were enrolled in this study from January 2012 to February 2013. All the patients were admitted to the Nemazee Hospital, affiliated to Shiraz University of Medical Sciences, Iran. They underwent transcranial Doppler (TCD) ultrasonography. Mean flow velocity (MFV) of basilar artery, vertebral artery, middle cerebral artery (MCA), anterior cerebral artery (ACA), and posterior cerebral artery (PCA) were evaluated.
RESULTS
A mean of patients' age was 67.80 ± 8.14 years. There were 83 men (49.1%) and 86 women (50.9%). Overall, 43 patients (25.4%), with a mean age of 66.7 ± 6.2 years, had intracranial stenosis. The number of men and women with intracranial stenosis was comparable (52.4% men vs. 47.6% women). Hypertension (P < 0.001), hyperlipidemia (P < 0.001), and diabetes mellitus (DM) (P < 0.001) were major risk factors for intracranial stenosis.
CONCLUSION
The prevalence of intracranial artery stenosis in patients with acute ischemic stroke is 25.4% which is comparable with previous reports from Iran and other Middle East countries.
背景
本研究旨在确定伊朗急性缺血性脑卒中患者颅内动脉狭窄的发生率。
方法
2012年1月至2013年2月，共有169例急性缺血性脑卒中患者符合参与条件并被纳入本研究。所有患者均入住伊朗设拉子医科大学附属内马齐医院。他们接受了经颅多普勒（TCD）超声检查。评估了基底动脉、椎动脉、大脑中动脉（MCA）、大脑前动脉（ACA）和大脑后动脉（PCA）的平均血流速度（MFV）。
结果
患者的平均年龄为67.80±8.14岁。男性83例（49.1%），女性86例（50.9%）。总体而言，43例患者（25.4%）存在颅内狭窄，平均年龄为66.7±6.2岁。颅内狭窄的男性和女性数量相当（男性52.4%，女性47.6%）。高血压（P<0.001）、高脂血症（P<0.001）和糖尿病（DM）（P<0.001）是颅内狭窄的主要危险因素。
结论
急性缺血性脑卒中患者颅内动脉狭窄的患病率为25.4%，与伊朗和其他中东国家先前的报道相当。
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