Ji Baochao, Xu Boyong, Guo Wentao, Rehei Aili, Mu Wenbo, Yang Desheng, Cao Li
Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, 137 South LiYuShan Road, Urumqi, Xinjiang, 830054, China.
Int Orthop. 2017 May;41(5):901-909. doi: 10.1007/s00264-016-3291-3. Epub 2016 Sep 20.
Removal of an infected prosthesis was considered the gold standard for eradication of infection. However, removal of well-fixed components can result in structural bone damage and compromised reconstruction. In these situations we questioned whether the infection after the total hip arthroplasty could be treated effectively and retain the well-fixed implant in a single-stage exchange.
A retrospective analysis which included 31 patients with chronic infected THA who underwent major partial single-stage revision, including routinely exchanged femoral head and liner components, aggressive soft tissue debridement, removal of the femoral stem or acetabular cup and retention of the well-fixed component, thorough exposed component brushing, and adequate surgical soaking. Powdered Vancomycin was poured into the surgical area and the infection control rate and clinical outcomes were evaluated. The failure to treat the infection was defined as a recurrence of infection in the same hip. The average follow-up was five years (2-15 years).
There were four (12.9 %) failures during the study period at an average of 15 months (9-21 months) after partial single-stage revision. Of the 31 patients, 27 (87.1 %) patients had a satisfactory outcome and required no additional surgical or medical treatment for recurrence of infection. Acetabular cups were revised in 22 patients and femoral stems in nine patients. The mean post-operative Harris hip score at the most recent assessment was 74.6 (68-82).
Treatment of chronic infected THA with retention of the well-fixed implant in a single-stage exchange can be fairly effective in the treatment of infection and achieving acceptable functional outcomes, which indicated that this may be an attractive alternative in highly selected patients.
Level IV, therapeutic study.
取出感染的假体被认为是根除感染的金标准。然而,取出固定良好的部件可能会导致结构性骨损伤和重建受损。在这些情况下,我们质疑全髋关节置换术后的感染能否在一期置换中得到有效治疗并保留固定良好的植入物。
一项回顾性分析,纳入了31例慢性感染性全髋关节置换术患者,他们接受了主要的部分一期翻修,包括常规更换股骨头和内衬部件、积极的软组织清创、取出股骨干或髋臼杯并保留固定良好的部件、彻底暴露部件刷洗以及充分的手术浸泡。将万古霉素粉末倒入手术区域,并评估感染控制率和临床结果。未能治疗感染被定义为同一髋关节感染复发。平均随访时间为5年(2 - 15年)。
在研究期间,有4例(12.9%)失败,平均发生在部分一期翻修后15个月(9 - 21个月)。在31例患者中,27例(87.1%)患者获得了满意的结果,无需因感染复发进行额外的手术或药物治疗。22例患者进行了髋臼杯翻修,9例患者进行了股骨干翻修。最近一次评估时的平均术后Harris髋关节评分为74.6(68 - 82)。
在一期置换中保留固定良好的植入物治疗慢性感染性全髋关节置换术,在治疗感染和实现可接受的功能结果方面可能相当有效,这表明在经过严格筛选的患者中这可能是一个有吸引力的选择。
IV级,治疗性研究。