Moreno J M, Rubio C E, Torres E A
Bol Asoc Med P R. 1989 Jun;81(6):214-8.
Although ulcerative colitis and Crohn's disease have been known for a long time, the etiology is still unknown, and at times it is difficult to distinguish one from the other. In addition, the characteristics of the disease make their epidemiologic study difficult. We have reviewed 70 cases with the diagnosis of Crohn's disease or ulcerative colitis, and compared our results with those published from other parts of the world. We found a high proportion of ulcerative colitis to Crohn's disease, 5.36:1. There was no difference in affected age groups or most frequent symptoms; but we found Crohn's disease to be more frequent in the colon. We also found a very low incidence of extraintestinal manifestations. We believe an adequate standard protocol should be followed for the evaluation of patients with inflammatory bowel disease, including complementary studies to assess disease patterns and complications.
尽管溃疡性结肠炎和克罗恩病已为人所知甚久,但其病因仍不明,且有时难以将两者区分开来。此外,该疾病的特点使其流行病学研究困难重重。我们回顾了70例诊断为克罗恩病或溃疡性结肠炎的病例,并将我们的结果与世界其他地区发表的结果进行了比较。我们发现溃疡性结肠炎与克罗恩病的比例很高,为5.36:1。在受影响的年龄组或最常见症状方面没有差异;但我们发现克罗恩病在结肠中更为常见。我们还发现肠外表现的发生率非常低。我们认为,对于炎症性肠病患者的评估应遵循适当的标准方案,包括进行补充研究以评估疾病模式和并发症。