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[急性阑尾炎的治疗:回顾性分析]

[Treatment of acute appendicitis: Retrospective analysis].

作者信息

Menclová K, Traboulsi E, Nikov A, Hána L, Rousek M, Ryska M

出版信息

Rozhl Chir. 2016 Fall;95(8):317-21.

Abstract

INTRODUCTION

Acute appendicitis is the most common cause of intra-abdominal emergency surgery worldwide. The approach to its treatment keeps changing. The number of acute appendectomies has been decreasing. Many patients are treated conservatively with success. Our study compares conservative and surgical treatment of acute appendicitis, including its complications in our department.

METHODS

We retrospectively analyzed the group of 117 patients hospitalized with the clinical diagnosis of acute appendicitis. We distinguished patients with complicated and uncomplicated appendicitis, and patients operated and treated conservatively. We evaluated complication rates and recurrences of the disease, respectively, in 1-year follow-up. The Student t test and Fishers exact test were used for the statistical analysis.

RESULTS

In 2012 we hospitalized 117 patients with acute appendicitis: 83 patients (71%) for uncomplicated and 34 (29%) for complicated appendicitis. 41% of patients with complicated and 13% with uncomplicated appendicitis (p=0.02) were treated conservatively. Conservative treatment or laparoscopic surgery, respectively, were used more often in women ( p0.001). There was no failure of conservative treatment. Perioperative morbidity was 13%. No patient died. 6 patients (24%) of the conservatively treated group were hospitalized in the subsequent year for recurrent problems. 4 (16%) were reoperated. The rate of negative appendectomy (negative pathological findings) was 11%. The hospitalization time was shorter in patients treated conservatively or using laparoscopy, respectively, compared to the group of patients undergoing appendectomy.

CONCLUSION

In the modern era of available complementary examinations and a broad spectrum of antibiotics the conservative approach is favoured as a treatment of complicated appendicitis. Conservative treatment of uncomplicated appendicitis is an option, but not the method of choice. Routine elective appendectomy after successful conservative treatment is groundless. Laparoscopic appendectomy is associated with lower morbidity than open appendectomy. Despite the available tests and scoring systems the negative appendectomy rate remains high.

KEY WORDS

appendicitis - appendectomy - laparoscopy - antibiotic treatment.

摘要

引言

急性阑尾炎是全球范围内腹腔内急诊手术最常见的病因。其治疗方法不断变化。急性阑尾切除术的数量一直在减少。许多患者接受保守治疗并取得成功。我们的研究比较了急性阑尾炎的保守治疗和手术治疗,包括我院该疾病的并发症情况。

方法

我们回顾性分析了117例临床诊断为急性阑尾炎的住院患者。我们区分了复杂性阑尾炎和非复杂性阑尾炎患者,以及接受手术治疗和保守治疗的患者。在1年的随访中,我们分别评估了疾病的并发症发生率和复发率。采用学生t检验和费舍尔精确检验进行统计分析。

结果

2012年,我们收治了117例急性阑尾炎患者:83例(71%)为非复杂性阑尾炎,34例(29%)为复杂性阑尾炎。41%的复杂性阑尾炎患者和13%的非复杂性阑尾炎患者(p = 0.02)接受了保守治疗。女性更常采用保守治疗或腹腔镜手术(p < 0.001)。保守治疗没有失败病例。围手术期发病率为13%。无患者死亡。保守治疗组中有6例(24%)患者在随后一年因复发问题再次住院。4例(16%)接受了再次手术。阴性阑尾切除术(病理检查结果为阴性)的发生率为11%。与接受阑尾切除术的患者组相比,接受保守治疗或腹腔镜手术的患者住院时间更短。

结论

在现有辅助检查手段和广谱抗生素的现代时代,保守治疗方法更适合作为复杂性阑尾炎的治疗方式。非复杂性阑尾炎的保守治疗是一种选择,但并非首选方法。保守治疗成功后常规进行择期阑尾切除术是没有根据的。腹腔镜阑尾切除术的发病率低于开腹阑尾切除术。尽管有可用的检查和评分系统,但阴性阑尾切除术的发生率仍然很高。

关键词

阑尾炎 - 阑尾切除术 - 腹腔镜检查 - 抗生素治疗

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