Satheeshkumar N, Vijayan R S K, Lingesh A, Santhikumar S, Vishnuvardhan Ch
Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hyderabad (NIPER-H), Balanagar, Hyderabad, 500037, Telangana, India.
Department of Chemistry, Temple University, Philadelphia, PA, 19122-1801, USA.
Adv Neurobiol. 2016;12:57-78. doi: 10.1007/978-3-319-28383-8_4.
India has traditionally been known to all over the world for spices and medicinal plants. Spices exhibit a wide range of pharmacological activities. In contemporary, Indian spices are used to rustle up delicious delicacies. However, the Indian spices are more than just adjuvant which adds aroma and fragrance to foods. A few spices are very widely used and grown commercially in many countries, contain many important chemical constituents in the form of essential oil, oleoresin, oleogum, and resins, which impart flavor, pungency, and color to the prepared dishes, simultaneously exerts diverse therapeutic benefits. Ayurveda, the traditional systems of medicine in India has many evidences for the utilization of spices to cure various diseases. Some of the activities have been scientifically proven. Among various indications central nervous system disorders are of prime importance and it has been evident in traditional books and published reports that spices in fact protect and cure neuronal ailments. Likewise there are many spices found in India used for culinary purpose and have been found to have reported specific activities against brain disorders. About 400 B.C., Hippocrates rightly said "Let food be thy medicine and medicine thy food." This review focuses on the importance of spices in therapeutics and the till date scientific findings of Indian spices in CNS pharmacology and explores the potential of Indian spices to cure CNS disorders.
印度传统上就因香料和药用植物而闻名于世。香料具有广泛的药理活性。在当代，印度香料被用于烹制美味佳肴。然而，印度香料不仅仅是为食物增添香气和香味的佐剂。一些香料在许多国家被广泛使用并进行商业种植，它们含有许多重要的化学成分，如精油、油树脂、油胶和树脂，这些成分赋予菜肴风味、辛辣味和颜色，同时还具有多种治疗功效。印度传统医学阿育吠陀有许多利用香料治疗各种疾病的证据。其中一些活性已经得到科学证实。在各种适应症中，中枢神经系统疾病至关重要，传统书籍和已发表的报告中都明确指出，香料实际上可以保护和治疗神经疾病。同样，在印度发现了许多用于烹饪的香料，并且已发现它们对脑部疾病具有特定的活性。大约在公元前400年，希波克拉底说得很对：“让食物成为你的药物，让药物成为你的食物。” 这篇综述重点关注香料在治疗方面的重要性以及印度香料在中枢神经系统药理学方面迄今为止的科学发现，并探讨印度香料治疗中枢神经系统疾病的潜力。
