Mättig H, Hartig W, Schindler H
Abteilung für Chirurgie des Kreiskrankenhauses Schkeuditz, DDR.
Gastroenterol J. 1989;49(1):3-7.
The lethal operative risk in gallbladder and bile duct operations decreased from 2.16% in the period 1964-1976 to 1.32% in the period 1979-1987.--Main operative risk factors are gallbladder and bile duct complications and the age beyond the 6th decade of life.--The lethality of choledocholithiasis actually amounts to the 37-fold of uncomplicated cholecystolithiasis and the lethality of all primary and secondary gallstone operations after the 6th decade of life amounts to the 38-fold in comparison with younger patients.--A further reduction of operative risk appears possible by reason: 1. Consequent early operation. 2. immediate operative or endoscopic removal of extrahepatic cholestasis, 3. complex intraoperative diagnostics of bile duct and papilla Vateri, 4. preoperative single dose AB prophylaxis or short-term therapy, 5. general low dose heparin prophylaxis, 6. primary endoscopic therapy in residual stones or irreversible stenosis of papilla Vateri and 7. interdisciplinary diagnosis and treatment of senile complications.
胆囊和胆管手术的致死性手术风险从1964 - 1976年期间的2.16%降至1979 - 1987年期间的1.32%。——主要手术风险因素是胆囊和胆管并发症以及60岁以上的年龄。——胆总管结石症的致死率实际上是单纯胆囊结石症的37倍,60岁以上患者所有原发性和继发性胆结石手术的致死率与年轻患者相比高达38倍。——手术风险进一步降低似乎是可能的,原因如下:1. 坚持早期手术。2. 立即进行手术或内镜下解除肝外胆汁淤积。3. 术中对胆管和十二指肠乳头进行复杂诊断。4. 术前单次剂量抗生素预防或短期治疗。5. 常规低剂量肝素预防。6. 对残留结石或十二指肠乳头不可逆狭窄进行原发性内镜治疗。7. 对老年并发症进行多学科诊断和治疗。