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[低风险新生儿C反应蛋白的测定]

[Determination of C-reactive protein in low-risk newborn infants].

作者信息

Baptista-González H A, Maciel-Corrales A L, Ibarra-Camacho A, Lozano-González C

出版信息

Bol Med Hosp Infant Mex. 1989 Jul;46(7):482-4.

PMID:2765162
Abstract

We present the results of the determination of C-reactive protein (CRP) in neonates with low risk of developing infection and without obstetric trauma. In determining the values of CRP we used the technique of latex agglutination. We included 56 neonates determining the changes in the values obtained in samples of cord blood and 24 hours. At birth, in 51 cases, the CRP was negative (0.91), 4 cases were positive at a dilution 1:4 (0.07) and one case at a dilution 1:8 (0.02). At 24 hours, in 47 cases (0.84) the CRP was negative; in 6 cases (0.04), at a dilution 1:8 and one more positive result at a dilution 1:6. There was not difference in the dilutions of the CRP in relation to the moment of sampling. We suggest that the method of latex agglutination is useful in sistemating the application use of CRP in neonates.

摘要

我们展示了对感染风险低且无产科创伤的新生儿进行C反应蛋白(CRP)测定的结果。在测定CRP值时,我们使用了乳胶凝集技术。我们纳入了56名新生儿,测定了脐血样本和出生后24小时所获值的变化。出生时,51例CRP为阴性(0.91),4例在1:4稀释度时为阳性(0.07),1例在1:8稀释度时为阳性(0.02)。24小时时,47例(0.84)CRP为阴性;6例(0.04)在1:8稀释度时为阳性,另有1例在1:6稀释度时为阳性。CRP的稀释度与采样时间无关。我们认为乳胶凝集法有助于规范CRP在新生儿中的应用。

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