Lee In Ho, Zan Elcin, Bell W Robert, Burger Peter C, Sung Heejong, Yousem David M
The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.; Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.
The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
J Korean Neurosurg Soc. 2016 Sep;59(5):466-70. doi: 10.3340/jkns.2016.59.5.466. Epub 2016 Sep 8.
To determine imaging features that may separate adamantinomatous and papillary variants of craniopharyngiomas given that tumors with adamantinomatous signature features are associated with higher recurrence rates, morbidity, and mortality. We specifically reviewed calcification on CT, T1 bright signal intensity, and cystic change on T2 weighted images for differentiating these two types.
We retrospectively reviewed the MRI and CT studies in 38 consecutive patients with pathologically proven craniopharyngiomas between January 2004 and February 2014 for the presence of calcification on CT scans, bright signal intensity on T1 weighted images, and cystic change on T2 weighted images.
Of the 38 craniopharyngiomas, 30 were adamantinomatous type and 8 were papillary type. On CT scans, calcification was present in 25 of 38 tumors. All calcified tumors were adamantinomatous type. Twenty four of 38 tumors had bright signal intensity on T1 weighted images. Of these 24 tumors, 22 (91.7%) were adamantinomatous and 2 were papillary type. Cystic change on T2 weighted images was noted in 37 of 38 tumors; only 1 tumor with papillary type did not show cystic change.
T1 bright signal intensity and calcification on CT scans uniformly favor the adamantinomatous type over papillary type of craniopharyngioma in children. However, these findings are more variable in adults where calcification and T1 bright signal intensity occur in 70.6% and 58.8% respectively of adult adamantinomatous types of craniopharyngiomas.
鉴于具有成釉细胞瘤特征的颅咽管瘤与较高的复发率、发病率和死亡率相关，确定可能区分颅咽管瘤的成釉细胞瘤型和乳头型的影像学特征。我们特别回顾了CT上的钙化、T1加权像上的高信号强度以及T2加权像上的囊性改变，以鉴别这两种类型。
我们回顾性分析了2004年1月至2014年2月间38例经病理证实的颅咽管瘤患者的MRI和CT研究，观察CT扫描上的钙化、T1加权像上的高信号强度以及T2加权像上的囊性改变。
38例颅咽管瘤中，30例为成釉细胞瘤型，8例为乳头型。在CT扫描上，38例肿瘤中有25例存在钙化。所有钙化肿瘤均为成釉细胞瘤型。38例肿瘤中有24例在T1加权像上呈高信号强度。在这24例肿瘤中，22例（91.7%）为成釉细胞瘤型，2例为乳头型。38例肿瘤中有37例在T2加权像上有囊性改变；只有1例乳头型肿瘤未显示囊性改变。
在儿童中颅咽管瘤的T1加权像高信号强度和CT扫描钙化均更倾向于成釉细胞瘤型而非乳头型。然而，在成人中这些表现变化更大，成人成釉细胞瘤型颅咽管瘤中分别有70.6%和58.8%出现钙化和T1加权像高信号强度。
Zotero 插件
