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颅咽管瘤的发病机制。

The pathogenesis of craniopharyngiomas.

作者信息

Prabhu Vikram C, Brown Henry G

机构信息

Department of Neurosurgery, Loyola University Medical Center, 2160, South 1st Avenue, Maywood, IL 60153, USA.

出版信息

Childs Nerv Syst. 2005 Aug;21(8-9):622-7. doi: 10.1007/s00381-005-1190-9. Epub 2005 Jun 18.

DOI:10.1007/s00381-005-1190-9
PMID:15965669
Abstract

OBJECTIVE

The objective of the study is to review the pathogenesis of craniopharyngiomas.

METHODS

A literature review of articles relating to the embryogenesis of the pituitary gland and sella and the pathogenesis of craniopharyngiomas was performed.

CONCLUSIONS

Craniopharyngiomas are benign, epithelial neoplasms of the sella and parasellar region seen in children and adults that may arise from neoplastic transformation of ectoderm-derived epithelial cell remnants of Rathke's pouch and the craniopharyngeal duct.

摘要

目的

本研究的目的是回顾颅咽管瘤的发病机制。

方法

对与垂体腺和蝶鞍的胚胎发生以及颅咽管瘤发病机制相关的文章进行文献综述。

结论

颅咽管瘤是儿童和成人中可见的蝶鞍及鞍旁区域的良性上皮性肿瘤，可能起源于拉特克囊和颅咽管外胚层来源的上皮细胞残余物的肿瘤转化。

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The pathogenesis of craniopharyngiomas.颅咽管瘤的发病机制。
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2
Ciliated craniopharyngioma--case report and pathological study.纤毛型颅咽管瘤——病例报告及病理研究。
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3
[Pituitary tumors].
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4
Lack of chromosomal imbalances in adamantinomatous and papillary craniopharyngiomas.成釉细胞瘤型和乳头型颅咽管瘤中缺乏染色体失衡。
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Jakob Erdheim (1874-1937): father of hypophyseal-duct tumors (craniopharyngiomas).雅各布·厄尔德海姆（1874 - 1937）：垂体管肿瘤（颅咽管瘤）之父。
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[Contribution to the pathogenesis of intrasellar and intraventricular cysts (author's transl)].
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Craniopharyngiomas in children: the pendulum moves again for an aggressive surgery-late complications and considerations with a recent series of 26 patients treated in Lyon.儿童颅咽管瘤：激进手术的趋势再次转变——近期里昂治疗的26例患者的晚期并发症及考量
Childs Nerv Syst. 2025 Apr 26;41(1):169. doi: 10.1007/s00381-025-06815-3.
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本文引用的文献

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HYPOPHYSEAL DUCT TUMORS: A REPORT OF THREE CASES AND A FOURTH CASE OF CYST OF RATHKE'S POUCH.垂体管肿瘤：三例报告及一例拉克氏囊囊肿病例
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Craniopharyngiomas.
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Craniopharyngiomas.
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一名患有造釉细胞瘤型颅咽管瘤的年轻成年人发生瘤内出血的罕见病例。
Radiol Case Rep. 2024 Nov 14;20(1):761-766. doi: 10.1016/j.radcr.2024.10.044. eCollection 2025 Jan.
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Unusual Presentation of Craniopharyngioma Pituitary Mass in a 71-Year-Old Female: A Case Report.71岁女性颅咽管瘤垂体肿块的不寻常表现：一例报告
Case Rep Endocrinol. 2024 Oct 4;2024:1333552. doi: 10.1155/2024/1333552. eCollection 2024.
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Beyond Epistaxis: A Rare Case of Ectopic Sinonasal Adamantinomatous Craniopharyngioma.鼻出血之外：一例罕见的异位鼻窦釉质型颅咽管瘤
Cureus. 2024 Sep 1;16(9):e68357. doi: 10.7759/cureus.68357. eCollection 2024 Sep.
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Topography and Radiological Variables as Ancillary Parameters for Evaluating Tissue Adherence, Hypothalamic-Pituitary Dysfunction, and Recurrence in Craniopharyngioma: An Integrated Multidisciplinary Overview.地形学和放射学变量作为评估颅咽管瘤组织粘连、下丘脑-垂体功能障碍及复发的辅助参数：综合多学科概述
Cancers (Basel). 2024 Jul 13;16(14):2532. doi: 10.3390/cancers16142532.
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A 55-Year-Old Woman Presenting with a Second Diagnosis of Craniopharyngioma Following Diagnosis and Successful Treatment of Craniopharyngioma as a 5-Year-Old Child.一位 55 岁女性，曾在 5 岁时被诊断为颅咽管瘤并成功治疗，此次因第二次诊断为颅咽管瘤而就诊。
Am J Case Rep. 2024 Jun 10;25:e943300. doi: 10.12659/AJCR.943300.
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Brachytherapy in craniopharyngiomas: a systematic review and meta-analysis of long-term follow-up.颅咽管瘤的近距离放疗：一项长期随访的系统评价和荟萃分析。
BMC Cancer. 2024 May 24;24(1):637. doi: 10.1186/s12885-024-12397-1.
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Exoscopic supraorbital approach for a suprasellar craniopharyngioma.经眶上外侧入路治疗鞍上颅咽管瘤
Neurosurg Focus Video. 2024 Jan 1;10(1):V5. doi: 10.3171/2023.10.FOCVID23140. eCollection 2024 Jan.
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Adamantinomatous craniopharyngioma: evolution in the management.骨 牙 型 颅咽管瘤：治疗方式的演变。
Childs Nerv Syst. 2023 Oct;39(10):2613-2632. doi: 10.1007/s00381-023-06143-4. Epub 2023 Sep 20.
The histogenesis and histology of an integumentary type of epithelium in the human hypophysis.
人类垂体中一种被覆型上皮的组织发生与组织学。
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Squamous-cell nests of the pituitary gland.垂体的鳞状细胞巢。
Cancer. 1955 May-Jun;8(3):623-8. doi: 10.1002/1097-0142(1955)8:3<623::aid-cncr2820080328>3.0.co;2-d.
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Squamous cell nests of the pituitary gland as related to the origin of craniopharyngiomas. A study of their presence in the newborn and infants up to age four.垂体鳞状细胞巢与颅咽管瘤起源的关系。对新生儿及4岁以下婴儿垂体鳞状细胞巢存在情况的研究。
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Sphenoclival Rathke's cleft cysts: embryology, clinical appearance and management.
Ear Nose Throat J. 1998 May;77(5):396-9, 403.
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Craniopharyngioma arising de novo in middle age. Case report.
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Epithelial cystic lesions of the sellar and parasellar region: a continuum of ectodermal derivatives?鞍区和鞍旁区域的上皮性囊性病变：外胚层衍生物的连续体？
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