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髋关节手术后医疗相关感染的发生率及危险因素

Incidence and Risk Factors for Health-Care Associated Infections after Hip Operation.

作者信息

Hessels Amanda J, Agarwal Mansi, Liu Jianfang, Larson Elaine L

机构信息

1 Columbia University , School of Nursing, New York, New York.

2 Columbia University , Mailman School of Public Health, New York, New York.

出版信息

Surg Infect (Larchmt). 2016 Dec;17(6):761-765. doi: 10.1089/sur.2016.062. Epub 2016 Sep 21.

Abstract

BACKGROUND

Hip operation reduces pain and improves mobility and quality of life for more than 300,000 people annually, most of whom are more than 65 years old. Substantial increases in surgical volume are projected between 2005 and 2030 in primary total (174%) and revision (137%) procedures. This projection demands that the impact of increasing age on the relative risk of health-care associated infections (HAI) after hip surgical procedures be assessed. Our aim was to examine the incidence and risk factors of HAI among patients who underwent hip operations between 2006 and 2012.

PATIENTS AND METHODS

This secondary analysis included data from patients 18 years old or older and having a hip prosthesis procedure in three New York City hospitals between 2006 and 2012. Procedures were categorized as total or partial hip replacements or revision and re-surfacing procedures. Outcomes of interest were blood stream infections (BSI), urinary tract infections (UTI), or surgical site infections (SSI). Patients in whom an infection developed during the hospital visit in which the hip procedure occurred were counted as cases.

RESULT

Of 2021 patients, approximately 11% (n = 218) had an HAI. There was no difference in infection rates by admission year despite an increase in surgical volume. SSI was associated with younger age, previous hospitalization, and hip revision surgical procedure whereas UTI and BSI were associated with older age, greater co-morbidity, longer pre-operative length of stay and intensive care unit stay, (p < 0.05).

CONCLUSION

HAI after hip operation affected approximately one in 10 patients over a 7-year period in three high-volume hospitals. SSI occurred least frequently, predominantly among patients who underwent revision surgery (without previous SSI), were younger, and had a history of previous hospitalization. Infections such as BSI and UTI, although rare, occurred more frequently and in patients with more co-morbidities, longer pre-operative length of stay, and who required higher level care. Further research to understand these unexpected findings and target interventions is warranted.

摘要

背景

每年有超过30万人接受髋关节手术,术后疼痛减轻,行动能力和生活质量得到改善,其中大多数患者年龄超过65岁。预计2005年至2030年期间,初次全髋关节置换手术(增长174%)和翻修手术(增长137%)的手术量将大幅增加。这一预测要求评估年龄增长对髋关节手术后医疗相关感染(HAI)相对风险的影响。我们的目的是研究2006年至2012年间接受髋关节手术患者的HAI发病率及危险因素。

患者与方法

这项二次分析纳入了2006年至2012年间在纽约市三家医院接受髋关节假体手术、年龄在18岁及以上患者的数据。手术分为全髋关节置换或半髋关节置换、翻修手术以及表面置换手术。感兴趣的结局包括血流感染(BSI)、尿路感染(UTI)或手术部位感染(SSI)。在进行髋关节手术的住院期间发生感染的患者计为病例。

结果

在2021例患者中,约11%(n = 218)发生了HAI。尽管手术量有所增加,但各入院年份的感染率并无差异。SSI与年龄较小、既往住院史以及髋关节翻修手术相关,而UTI和BSI与年龄较大、合并症较多、术前住院时间和重症监护病房住院时间较长相关(p < 0.05)。

结论

在三家大型医院中,髋关节手术后的HAI在7年期间影响了约十分之一的患者。SSI发生频率最低,主要发生在接受翻修手术(无既往SSI)、年龄较小且有既往住院史的患者中。BSI和UTI等感染虽然罕见,但在合并症更多、术前住院时间更长且需要更高水平护理的患者中发生频率更高。有必要进行进一步研究以了解这些意外发现并针对性地采取干预措施。

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本文引用的文献

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Risk Prediction Tools for Hip and Knee Arthroplasty.髋关节和膝关节置换术的风险预测工具
J Am Acad Orthop Surg. 2016 Jan;24(1):19-27. doi: 10.5435/JAAOS-D-15-00072.
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The learning curve for hip arthroscopy: a systematic review.髋关节镜手术学习曲线:系统评价。
Arthroscopy. 2014 Mar;30(3):389-97. doi: 10.1016/j.arthro.2013.11.012. Epub 2014 Jan 22.
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Learning curve of basic hip arthroscopy technique: CUSUM analysis.基础髋关节镜技术的学习曲线:CUSUM 分析。
Knee Surg Sports Traumatol Arthrosc. 2013 Aug;21(8):1940-4. doi: 10.1007/s00167-012-2241-x. Epub 2012 Oct 18.

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