McCullagh R, Dillon C, Dahly D, Horgan N F, Timmons S
Centre for Gerontology & Rehabilitation, @St Finbarr's Hospital, College of Medicine and Health, University College Cork, Cork, Ireland.
Physiol Meas. 2016 Oct;37(10):1872-1884. doi: 10.1088/0967-3334/37/10/1872. Epub 2016 Sep 21.
Evidence suggests that inactivity during a hospital stay is associated with poor health outcomes in older medical inpatients. We aimed to estimate the associations of average daily step-count (walking) in hospital with physical performance and length of stay in this population. Medical in-patients aged ⩾65 years, premorbidly mobile, with an anticipated length of stay ⩾3 d, were recruited. Measurements included average daily step-count, continuously recorded until discharge, or for a maximum of 7 d (Stepwatch Activity Monitor); co-morbidity (CIRS-G); frailty (SHARE F-I); and baseline and end-of-study physical performance (short physical performance battery). Linear regression models were used to estimate associations between step-count and end-of-study physical performance or length of stay. Length of stay was log transformed in the first model, and step-count was log transformed in both models. Similar models were used to adjust for potential confounders. Data from 154 patients (mean 77 years, SD 7.4) were analysed. The unadjusted models estimated for each unit increase in the natural log of step-count, the natural log of length of stay decreased by 0.18 (95% CI -0.27 to -0.09). After adjustment of potential confounders, while the strength of the inverse association was attenuated, it remained significant (β = -0.15, 95%CI -0.26 to -0.03). The back-transformed result suggested that a 50% increase in step-count was associated with a 6% shorter length of stay. There was no apparent association between step-count and end-of-study physical performance once baseline physical performance was adjusted for. The results indicate that step-count is independently associated with hospital length of stay, and merits further investigation.
有证据表明,住院期间缺乏活动与老年内科住院患者的不良健康结局相关。我们旨在评估该人群住院期间平均每日步数(行走)与身体机能及住院时长之间的关联。招募了年龄≥65岁、病前可活动、预期住院时长≥3天的内科住院患者。测量指标包括平均每日步数(使用步数监测活动仪持续记录直至出院,或最长记录7天)、共病情况(CIRS - G)、衰弱程度(SHARE F - I)以及基线和研究结束时的身体机能(简短身体机能量表)。使用线性回归模型评估步数与研究结束时身体机能或住院时长之间的关联。在第一个模型中对住院时长进行对数转换,在两个模型中都对步数进行对数转换。使用类似模型对潜在混杂因素进行调整。分析了154例患者(平均年龄77岁,标准差7.4)的数据。未调整模型估计,步数自然对数每增加一个单位,住院时长自然对数减少0.18(95%置信区间为 - 0.27至 - 0.09)。在对潜在混杂因素进行调整后,虽然反向关联的强度有所减弱,但仍然显著(β = - 0.15,95%置信区间为 - 0.26至 - 0.03)。反转换结果表明,步数增加50%与住院时长缩短6%相关。在对基线身体机能进行调整后,步数与研究结束时身体机能之间没有明显关联。结果表明,步数与住院时长独立相关,值得进一步研究。