Gu Jiayi, Chao Jianqian, Chen Wenji, Xu Hui, Wu Zhenchun, Chen Huanghui, He Tingting, Deng Lin, Zhang Ruizhi
Key Laboratory of Environmental Medicine Engineering of Ministry of Education, Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China.
Zhongda Hospital, Affiliated to Southeast University, Nanjing, Jiangsu, China.
Arch Gerontol Geriatr. 2017 Jan-Feb;68:62-67. doi: 10.1016/j.archger.2016.09.001. Epub 2016 Sep 14.
The primary objective of the study was to investigate the prevalence and patterns of multimorbidity in the community-dwelling elderly in urban China.
By a cluster random sampling method, 2452 persons aged 60 years and older were enrolled as the subjects in an urban community in Nanjing, China. Data on 13 chronic diseases were collected by interviews, physical check-ups and support by physicians. Factor analyses and the logistic regression models were performed to analyze the patterns of multimorbidity.
The prevalence of multimorbidity was 49.4% in the community-dwelling elderly in urban China. The observed prevalence of 6 chronic disease pairs was higher than their expected prevalence, including hypertension and diabetes, hypertension and coronary heart disease, hypertension and dyslipidaemia, diabetes and cataract, diabetes and hearing disorder, hypertension and stroke. Three patterns were detected as follows: the first pattern with a prevalence of 9.5% covered degenerative diseases (hearing disorder, cataract, joint disease) and cancer; The second pattern with a prevalence of 1.7% was characterized by liver disease, lung disease, gastrointestinal disease; And the third pattern with a prevalence of 22.4% was characterized by cardiovascular diseases (dyslipidaemia, hypertension, coronary heart disease), metabolic diseases (diabetes) and kidney disease. Compared with <70 years, ≥80 years were found as the risk factor of the prevalence of three patterns.
A significant proportion of elderly populations was affected by multimorbidity in urban China. Specific patterns of multimorbidity were found at group level and the prevalence was associated with age.
本研究的主要目的是调查中国城市社区老年人中多病共存的患病率及模式。
采用整群随机抽样方法，选取中国南京一个城市社区的2452名60岁及以上的老人作为研究对象。通过访谈、体格检查并在医生的协助下收集了13种慢性病的数据。进行因子分析和逻辑回归模型以分析多病共存的模式。
中国城市社区老年人中多病共存的患病率为49.4%。观察到的6种慢性病组合的患病率高于预期患病率，包括高血压和糖尿病、高血压和冠心病、高血压和血脂异常、糖尿病和白内障、糖尿病和听力障碍、高血压和中风。检测到三种模式如下：第一种模式患病率为9.5%，涵盖退行性疾病（听力障碍、白内障、关节疾病）和癌症；第二种模式患病率为1.7%，其特征为肝病、肺病、胃肠病；第三种模式患病率为22.4%，其特征为心血管疾病（血脂异常、高血压、冠心病）、代谢疾病（糖尿病）和肾病。与<70岁相比，≥80岁被发现是三种模式患病率的危险因素。
在中国城市，相当一部分老年人群受到多病共存的影响。在群体层面发现了多病共存的特定模式，且患病率与年龄相关。
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