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中国南方社区居住老年人中与功能独立性相关的多重疾病:一项横断面研究

Multimorbidity associated with functional independence among community-dwelling older people: a cross-sectional study in Southern China.

作者信息

Wang Xiao-Xiao, Lin Wei-Quan, Chen Xu-Jia, Lin Ying-Yu, Huang Ling-Ling, Zhang Sheng-Chao, Wang Pei-Xi

机构信息

Institute of Public Health, School of Nursing, Henan University, Kaifeng, 475004, China.

Guangzhou Center for Disease Control and Prevention, Guangzhou, 510440, China.

出版信息

Health Qual Life Outcomes. 2017 Apr 17;15(1):73. doi: 10.1186/s12955-017-0635-7.

Abstract

BACKGROUND

Multimorbidity, the coexistence of two or more chronic diseases, is common in older adults. And it may lead to many adverse health outcomes, such as disability. However, data on multimorbidity and its relationship with functional independence are scarce in Asian countries. Therefore, this study aims to investigate the relationship between multimorbidity and functional status among older people in China.

METHODS

Based on a cross-sectional survey, the information regarding 2705 older adults, who were of at least 60 years of age, was collected through interviews and analyzed. To assess functional status, we used the Functional Independence Measure (FIM). Exploratory factor analysis was performed to assess correlations among chronic diseases. Several logistic regression models were run in the study.

RESULTS

The presence of two or more chronic conditions and the number of multimorbidity group overlaps were independent risk factors for the loss of functional independence in older adults. Hypertension and chronic pain, emerged as the most prevalent multimorbidity pair, was significantly associated with functional independence (OR = 1.64, 95% CI = 1.25-2.16), followed by the co-occurrence of hypertension and heart diseases with a lower prevalence but a higher OR compared with the former pair (OR = 1.72, 95% CI = 1.15-2.58). Of the five multimorbidity groups used for factor analysis, the bones and pain group (OR = 1.47, 95% CI = 1.23-1.77) and the cardiometabolic group (OR = 1.34, 95% CI = 1.13-1.59) were both found to be significantly correlated with lower functional independence.

CONCLUSIONS

Multimorbidity was common among older people in Southern China. Studying the relationship between multimorbidity and functional status could be useful to find potential correlations among chronic diseases. Additionally, it may also be meaningful to identify multimorbidity combinations, posing an increased risk of loss of functional independence, and further improve functional status in older adults with comorbidities.

摘要

背景

多种慢性病共存,即患两种或更多种慢性病,在老年人中很常见。它可能导致许多不良健康后果,如残疾。然而,亚洲国家关于多种慢性病及其与功能独立性之间关系的数据很少。因此,本研究旨在调查中国老年人中多种慢性病与功能状态之间的关系。

方法

基于一项横断面调查,通过访谈收集了2705名年龄至少为60岁的老年人的信息并进行分析。为评估功能状态,我们使用了功能独立性测量量表(FIM)。进行探索性因素分析以评估慢性病之间的相关性。本研究运行了几个逻辑回归模型。

结果

存在两种或更多种慢性病以及多种慢性病组重叠数量是老年人功能独立性丧失的独立危险因素。高血压和慢性疼痛是最常见的多种慢性病组合,与功能独立性显著相关(比值比[OR]=1.64,95%置信区间[CI]=1.25 - 2.16),其次是高血压和心脏病同时存在,其患病率较低但OR值高于前一组(OR = 1.72,95% CI = 1.15 - 2.58)。在用于因素分析的五个多种慢性病组中,骨骼与疼痛组(OR = 1.47,95% CI = 1.23 - 1.77)和心脏代谢组(OR = 1.34,95% CI = 1.13 - 1.59)均与较低的功能独立性显著相关。

结论

多种慢性病在中国南方老年人中很常见。研究多种慢性病与功能状态之间的关系可能有助于发现慢性病之间的潜在相关性。此外,识别出功能独立性丧失风险增加的多种慢性病组合,并进一步改善患有合并症的老年人的功能状态可能也具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/877d/5392938/c85b7fac652b/12955_2017_635_Fig1_HTML.jpg

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