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认知康复和支持性就业对精神疾病患者的成本效益:一项随机对照试验。

Cost-effectiveness of cognitive remediation and supported employment for people with mental illness: a randomized controlled trial.

作者信息

Yamaguchi S, Sato S, Horio N, Yoshida K, Shimodaira M, Taneda A, Ikebuchi E, Nishio M, Ito J

机构信息

Department of Psychiatric Rehabilitation,National Institute of Mental Health, National Center of Neurology and Psychiatry,Kodaira,Japan.

Department of Social Welfare, Faculty of Human and Social Sciences,Showa Women's University,Setagaya,Tokyo,Japan.

出版信息

Psychol Med. 2017 Jan;47(1):53-65. doi: 10.1017/S0033291716002063. Epub 2016 Sep 22.

Abstract

BACKGROUND

Little is known about the economic benefits of cognitive remediation and supported employment (CR + SE). The present study aimed to investigate the cost-effectiveness of CR + SE compared with traditional vocational services (TVS).

METHOD

Individuals with mental illness and low cognitive function were recruited at six sites in Japan. A total of 111 participants were randomly allocated to the CR + SE group or the TVS group. Clinical and vocational outcomes were assessed at baseline and 12-month follow-up. Service utilization data were collected monthly. The data on outcomes and costs were combined to examine cost-effectiveness.

RESULTS

The data were obtained from a total of 92 participants. The CR + SE group resulted in better vocational and clinical outcomes (employment rate, 62.2%; work tenures, 78.6 days; cognitive improvement, 0.5) than the TVS group (19.1%, 24.9 days and 0.2). There was no significant difference in mean total costs between the groups (CR + SE group: $9823, s.d. = $6372, TVS group: $11 063, s.d. = $11 263) with and without adjustment for covariates. However, mean cost for medical services in the CR + SE group was significantly lower than that in the TVS group after adjusting covariates (Β = -$3979, 95% confidence interval -$7816 to -$143, p = 0.042). Cost-effectiveness acceptability curves for vocational outcomes illustrated the high probabilities (approximately 70%) of the CR + SE group being more cost-effective than TVS when society is not willing to pay additional costs.

CONCLUSIONS

CR + SE appears to be a cost-effective option for people with mental illness who have low cognitive functioning when compared with TVS.

摘要

背景

关于认知康复与支持性就业(CR + SE)的经济效益知之甚少。本研究旨在调查CR + SE与传统职业服务(TVS)相比的成本效益。

方法

在日本的六个地点招募了患有精神疾病且认知功能低下的个体。总共111名参与者被随机分配到CR + SE组或TVS组。在基线和12个月随访时评估临床和职业结局。每月收集服务利用数据。将结局和成本数据相结合以检查成本效益。

结果

数据来自总共92名参与者。CR + SE组在职业和临床结局方面(就业率62.2%;工作任期78.6天;认知改善0.5)比TVS组(19.1%、24.9天和0.2)更好。在调整协变量前后,两组之间的平均总成本没有显著差异(CR + SE组:9823美元,标准差 = 6372美元,TVS组:11063美元,标准差 = 11263美元)。然而,在调整协变量后,CR + SE组的医疗服务平均成本显著低于TVS组(Β = -3979美元,95%置信区间 -7816美元至 -143美元,p = 0.042)。职业结局的成本效益可接受性曲线表明,当社会不愿意支付额外成本时,CR + SE组比TVS组更具成本效益的概率很高(约70%)。

结论

与TVS相比,CR + SE对于认知功能低下的精神疾病患者似乎是一种具有成本效益的选择。

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