Zhao Y F, Wang Z Q, Yang J, Li Y C, Yin P, You J L, Zhou M G
National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2016 Sep 6;50(9):769-775. doi: 10.3760/cma.j.issn.0253-9624.2016.09.005.
To analyze the burden of disease attributed to high fasting plasma glucose(FPG)in China in 1990 and 2013. The analysis used data obtained from the 2013 Global Burden of Diseases Study and examined deaths, death rate, disability-adjusted life years(DALY), years lived with disability(YLD)and years of life lost(YLL)attributed to high FPG in 1990 and 2013 in China(not including Taiwan, China). An average world population age-structure for the period 2000- 2025 was adopted to calculate age-standardized rates. In 2013, the number of deaths attributed to high FPG in China increased to 621.9 thousand from 320.3 thousand in 1990. From 1990- 2013, the age-standardized death rate attributable to high FPG increased from 45.69/100 000 to 48.64/100 000. DALYs caused by high FPG increased to 20.389 1 million in 2013 from 10.648 3 million in 1990. In 2013, high FPG caused 8.751 5 million YLD and 11.637 6 million YLL, and the percentage of YLL in DALY decreased to 57.1% in 2013 from 68.7% in 1990. Compared with 1990, the age-standardized DALY rate attributed to high FPG increased by 10.81%. In 2013, the top three provinces with the highest burden of disease attributed to high FPG were Xinjiang, Jilin and Liaoning provinces, with standardized death rates of 83.38, 74.01 and 68.64/100 000, respectively, and the standardized DALY rate was 2 217.96, 2 001.84 and 1 837.79/100 000 in the three provinces, respectively. Compared with 1990, the burden of disease attributed to high FPG in 2013 increased substantially in China, in particular the burden of attributed YLD. However, the burden of YLL attributed to high FPG has decreased modestly. The burden of disease caused by high FPG shows variation among different provinces in China.
分析1990年和2013年中国空腹血糖升高（FPG）所致的疾病负担。该分析使用了从2013年全球疾病负担研究中获得的数据，研究了1990年和2013年中国（不包括中国台湾）因FPG升高导致的死亡、死亡率、伤残调整生命年（DALY）、带病生存年数（YLD）和寿命损失年数（YLL）。采用2000 - 2025年期间的世界平均人口年龄结构来计算年龄标准化率。2013年，中国因FPG升高导致的死亡人数从1990年的32.03万增加到62.19万。1990 - 2013年，因FPG升高导致的年龄标准化死亡率从45.69/10万上升至48.64/10万。FPG升高导致的DALYs从1990年的1064.83万增加到2013年的2038.91万。2013年，FPG升高导致875.15万YLD和1163.76万YLL，YLL在DALY中的占比从1990年的68.7%降至2013年的57.1%。与1990年相比，因FPG升高导致的年龄标准化DALY率上升了10.81%。2013年，FPG所致疾病负担最高的前三个省份是新疆、吉林和辽宁，标准化死亡率分别为83.38/10万、74.01/10万和68.64/10万，三省的标准化DALY率分别为2217.96/10万、2001.84/10万和1837.79/10万。与1990年相比，2013年中国FPG所致的疾病负担大幅增加，尤其是YLD所致负担。然而，FPG所致的YLL负担略有下降。FPG所致疾病负担在中国不同省份之间存在差异。
