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关节镜下切除马腕骨碎片骨折后,通过关节内注射脂肪来源的基质血管成分成功治疗。

Successful management of an equine carpal chip fracture by intra-articularly injected adipose-derived stromal vascular fraction after arthroscopic removal.

作者信息

Tyrnenopoulou P, Karayannopoulou M, Angelopoulou S, Pyrros A, Mparous E, Koliakos G, Diakakis N

机构信息

Post-Graduate Student, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 546 27 Thessaloniki, Greece;

Department of Clinical Studies, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 546 27 Thessaloniki, Greece;

出版信息

Iran J Vet Res. 2016 Winter;17(1):59-61.

Abstract

Carpal chip fractures are common causes of lameness in racehorses. Due to disadvantages in surgical management, adjuvant treatment modalities are usually necessary. Adipose-derived stem cells (ADSCs) have the potential to differentiate into other cell types including bone and cartilage cells. Adipose-derived stromal vascular fraction (SVF) is produced during ADSCs isolation from adipose tissue. The purpose of this report was to present the successful management of a grade III chip fracture in the right carpus of a 5-year-old Thoroughbred gelding by intra-articularly injected autologous SVF one month after the arthroscopic removal of the fracture. This treatment resulted in lameness improvement and short rehabilitation period to previous racing activities. High performance levels and no recurrent injuries were recorded during a twenty month follow-up period.

摘要

腕骨碎片骨折是赛马跛行的常见原因。由于手术治疗存在缺点,通常需要辅助治疗方式。脂肪来源干细胞(ADSCs)有分化为包括骨细胞和软骨细胞在内的其他细胞类型的潜力。脂肪来源的基质血管成分(SVF)是在从脂肪组织中分离ADSCs的过程中产生的。本报告的目的是介绍一匹5岁纯种马 gelding右腕关节III级碎片骨折的成功治疗情况,即在关节镜下取出骨折碎片一个月后,通过关节内注射自体SVF进行治疗。这种治疗使跛行情况得到改善,恢复到之前赛马活动的康复期缩短。在20个月的随访期内,记录到其表现出高水平的运动能力且没有再次受伤。

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