Das Rumpa, Nath Gorakh, Bohara Sangita, Bhattacharya Aarti Biswajit, Gupta Vivek
Assistant Professor, Department of Pathology, Hind Institute of Medical Sciences , Barabanki, India .
Clinician Incharge, Department of Otorhinolaryngology, Nath ENT Centre , Faizabad, India .
J Clin Diagn Res. 2016 Aug;10(8):ED21-2. doi: 10.7860/JCDR/2016/19753.8374. Epub 2016 Aug 1.
Acinic Cell Carcinoma (AcCC) is a slow growing, malignant tumour of salivary glands, predominantly found in parotid gland and rarely in submandibular gland or minor salivary glands. Rarely, the tumour can arise in Heterotopic Salivary Gland Tissue (HSGT) and can present bilaterally. Synchronous contralateral tumour or tumour arising in HSGT is easily missed clinically. Fine Needle Aspiration Cytology (FNAC) is an important preoperative diagnostic investigation in cases of AcCC. Sometimes its diagnosis on cytology is very difficult and it is easily misdiagnosed as benign, affecting the long term prognosis. Here, we present two unusual cases of AcCC. One developed in HSGT and the other was synchronous bilateral. Though the histological features of AcCC appear to be characteristic but clinical suspicion and cytological features have been described as equally important for preoperative diagnosis. Present cases highlight the importance of a cytopathologist who plays an important role in its preliminary diagnosis.
腺泡细胞癌（AcCC）是一种生长缓慢的唾液腺恶性肿瘤，主要发生于腮腺，很少见于下颌下腺或小唾液腺。罕见情况下，肿瘤可起源于异位唾液腺组织（HSGT），并可双侧发生。临床上，同步对侧肿瘤或起源于HSGT的肿瘤很容易被漏诊。细针穿刺细胞学检查（FNAC）是AcCC病例重要的术前诊断检查方法。有时其细胞学诊断非常困难，容易被误诊为良性，从而影响长期预后。在此，我们报告两例不寻常的腺泡细胞癌病例。一例发生于HSGT，另一例为同步双侧发病。尽管腺泡细胞癌的组织学特征似乎具有特异性，但临床怀疑和细胞学特征对于术前诊断同样重要。目前的病例突出了细胞病理学家在其初步诊断中所起的重要作用。
