Shinde Gauri Raghunath, Vaswani Babita Prakash, Patange R P, Laddad Manisha Manish, Bhosale Rajashree Babasaheb
Assistant Professor, Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences Deemed University , Karad, Maharashtra, India .
Junior Resident, Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences Deemed University , Karad, Maharashtra, India .
J Clin Diagn Res. 2016 Aug;10(8):QC04-7. doi: 10.7860/JCDR/2016/19247.8288. Epub 2016 Aug 1.
Placental abruption complicates about 1% of singleton pregnancies and is an important cause of perinatal mortality and morbidity. Though sensitivity and reliability of ultrasound are poor for detecting or excluding placental abruption, because of the advances in ultrasound resolution, imaging and interpretation, sensitivity of ultrasound is better than what was reported previously.
To determine the diagnostic performance of Ultrasonography (USG) for the detection of placental abruption and whether sonographic results correlate with maternal and foetal management and outcome.
Thirty patients with clinical diagnosis of placental abruption were studied in the Obstetrics and Gynaecology Department of Krishna Institute of Medical Sciences, over a period of 6 months. These patients underwent ultrasonography for confirmation. Obstetric and neonatal outcome and sonographic results were compared and reviewed. Sonographic sensitivity and specificity and positive and negative predictive values were calculated.
Incidence of abruption in present study was 1.56% (28 patients out of 1786 total deliveries). Sensitivity of ultrasonography in the diagnosis of abruption was 57% (CI 37.15%-75.57%) while its specificity was 100% (CI 15.81%-100%) with a positive predictive value of 100% (CI 79.42%-100%) and a 14% (CI 1.78% - 42.83%) negative predictive value. An 87.5% of patients(14 out of 16) with a positive USG finding of abruption had Intrauterine foetal Death (IUD)/still birth while 91.6% of patients (11 out of 12) with negative USG findings of abruption gave birth to babies who required NICU admission.
Sonography is not sensitive for the detection of placental abruption but it is highly specific. Positive sonographic findings are associated with increased maternal morbidity, require more aggressive obstetric management and it is associated with worse perinatal outcome. In case of a negative USG finding, but a strong clinical suspicion of abruption if obstetric intervention is made in due time, foetal as well as maternal outcome are better. Foetal outcome also depends on gestational age. Preterm patients with positive USG and intrapartum findings of abruption have worse foetal outcome compared to full-term patients with abruption.
胎盘早剥在单胎妊娠中约占1%,是围产期死亡率和发病率的重要原因。尽管超声检测或排除胎盘早剥的敏感性和可靠性较差,但由于超声分辨率、成像和解读技术的进步,超声的敏感性比之前报道的有所提高。
确定超声检查(USG)对胎盘早剥的诊断效能,以及超声检查结果是否与母体和胎儿的管理及结局相关。
在克里希纳医学科学研究所妇产科,对30例临床诊断为胎盘早剥的患者进行了为期6个月的研究。这些患者接受了超声检查以确诊。比较并回顾了产科和新生儿结局以及超声检查结果。计算了超声检查的敏感性、特异性、阳性预测值和阴性预测值。
本研究中胎盘早剥的发生率为1.56%(1786例总分娩中有28例)。超声检查诊断胎盘早剥的敏感性为57%(可信区间37.15%-75.57%),特异性为100%(可信区间15.81%-100%),阳性预测值为100%(可信区间79.42%-100%),阴性预测值为14%(可信区间1.78%-42.83%)。超声检查胎盘早剥阳性的患者中,87.5%(16例中的14例)发生了宫内胎儿死亡(IUD)/死产,而超声检查胎盘早剥阴性的患者中,91.6%(12例中的11例)分娩的婴儿需要入住新生儿重症监护病房(NICU)。
超声检查对胎盘早剥的检测不敏感,但具有高度特异性。超声检查阳性结果与母体发病率增加相关,需要更积极的产科管理,且与更差的围产期结局相关。如果超声检查结果为阴性,但临床高度怀疑胎盘早剥,及时进行产科干预,胎儿和母体的结局会更好。胎儿结局还取决于孕周。与足月胎盘早剥患者相比,超声检查阳性且产时发现胎盘早剥的早产患者的胎儿结局更差。