Obradović O, Bogdanović D, Cvetković D, Pesić V, Petrović V, Dozić S
Bull Group Int Rech Sci Stomatol Odontol. 1989 Jun;32(2):105-10.
50 corpses from adults aged 20 to 75 have been used in order to study the atherosclerotic lesions occurring in typical regions (bifurcation of the common carotid artery and the abdominal aorta) and their relationship to atherosclerotic changes in the inferior alveolar artery. Histological analysis revealed that atherosclerotic alterations of the inferior alveolar artery may appear sometimes earlier than it would be expected on the ground of age. Intima cell proliferation and thickening of elastic elements in the middle layer of the arterial wall, the first signs of atherosclerosis, were found already at the beginning of the third decade of life when the signs of this process in the typical regions were not yet evident. Atherosclerosis affects essentially the functional capacity of the inferior alveolar artery. The development of atherosclerosis in the wall of this artery favours an hypovascularization of the mandible, which must be of certain importance in every operative procedure in oral surgery, especially in those inducing a severe and long traumatism in bone and soft tissues, such as dental implantations.
为了研究典型区域（颈总动脉分叉处和腹主动脉）出现的动脉粥样硬化病变及其与下牙槽动脉粥样硬化变化的关系，使用了50具年龄在20至75岁之间的成年人尸体。组织学分析显示，下牙槽动脉的动脉粥样硬化改变有时可能比根据年龄预期的出现得更早。动脉壁中层内膜细胞增殖和弹性成分增厚是动脉粥样硬化的最初迹象，在生命第三个十年开始时就已发现，而此时典型区域的这一过程迹象尚不明显。动脉粥样硬化本质上会影响下牙槽动脉的功能能力。该动脉壁中动脉粥样硬化的发展有利于下颌骨血管减少，这在口腔外科的每一个手术过程中都必定具有一定重要性，尤其是在那些会对骨骼和软组织造成严重且长期创伤的手术中，如牙种植术。
