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[优化老年人药物治疗管理的策略]

[Strategies to optimize pharmacological management in older adults].

作者信息

Casas-Vásquez Paola, Ortiz-Saavedra Pedro, Penny-Montenegro Eduardo

出版信息

Rev Peru Med Exp Salud Publica. 2016 Jun;33(2):335-41.

PMID:27656935
Abstract

Population aging increases the prevalence of chronic and multiple morbid illnesses and increases the consumption of multiple medications and related problems accordingly. It is reported that >50% of dispensed medications are consumed by older adults; in fact, >80% of older adults take at least one medication daily and 75% do not inform their doctor that they are using unconventional treatments. Appropriate medication prescription to older adults is challenging and it requires the consideration of risks and benefits of the indicated medications, for which clear evidence of their efficacy is often lacking due to the limited inclusion of elderly populations in randomized clinical trials on which clinical guides are based for chronic disease management. However, general guidelines and recommendations must be comprehensively implemented and supported by a multidisciplinary team whenever pharmacological management is provided for older adults. Here we focus on promoting proper prescriptions according to evidence-based recommendations to reduce inappropriate prescriptions, polypharmacy, and self-medication.

摘要

人口老龄化增加了慢性和多种疾病的患病率,相应地增加了多种药物的使用量及相关问题。据报道,超过50%的配药由老年人服用;事实上,超过80%的老年人每天至少服用一种药物,75%的老年人未告知医生他们正在使用非传统治疗方法。为老年人开具合适的药物处方具有挑战性,这需要考虑所开药物的风险和益处,由于在作为慢性病管理临床指南基础的随机临床试验中纳入老年人群体有限,往往缺乏其疗效的确切证据。然而,每当为老年人提供药物治疗管理时,多学科团队必须全面实施并支持一般指南和建议。在此,我们专注于根据循证建议促进合理处方,以减少不适当处方、多重用药和自我药疗。

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[Strategies to optimize pharmacological management in older adults].[优化老年人药物治疗管理的策略]
Rev Peru Med Exp Salud Publica. 2016 Jun;33(2):335-41.
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Tools to reduce polypharmacy.减少多种药物治疗的工具。
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Prescription of potentially inappropriate medication in Korean older adults based on 2012 Beers Criteria: a cross-sectional population based study.基于2012年Beers标准的韩国老年人潜在不适当用药情况:一项基于人群的横断面研究。
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Intervention to Improve Appropriate Prescribing and Reduce Polypharmacy in Elderly Patients Admitted to an Internal Medicine Unit.改善内科病房老年患者合理用药及减少多重用药的干预措施
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J Am Geriatr Soc. 2019 Feb;67(2):371-380. doi: 10.1111/jgs.15634. Epub 2018 Dec 7.

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