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危地马拉西南部接受血液透析患者中非传统病因慢性肾脏病的患病率

Prevalence of chronic kidney disease of non-traditional causes in patients on hemodialysis in southwest Guatemala.

作者信息

Laux Timothy S, Barnoya Joaquin, Cipriano Ever, Herrera Erick, Lopez Noemi, Polo Vicente Sanchez, Rothstein Marcos

出版信息

Rev Panam Salud Publica. 2016 Apr;39(4):186-93.

Abstract

Objective To document the prevalence of patients on hemodialysis in southwestern Guatemala who have chronic kidney disease (CKD) of non-traditional causes (CKDnt). Methods This cross-sectional descriptive study interviewed patients on hemodialysis at the Instituto Guatemalteco de Seguridad Social on their health and occupational history. Laboratory serum, urine and vital sign data at the initiation of hemodialysis were obtained from chart reviews. Patients were classified according to whether they had hypertension or obesity or neither. The proportion of patients with and without these traditional CKD risk factors was recorded and the association between demographic and occupational factors and a lack of traditional CKD risk factors analyzed using multivariate logistic regression. Results Of 242 total patients (including 171 non-diabetics) enrolled in hemodialysis in southwestern Guatemala, 45 (18.6% of total patients and 26.3% of non-diabetics) lacked traditional CKD risk factors. While agricultural work history was common, only travel time greater than 30 minutes and age less than 50 years old were significantly associated with CKD in the absence of traditional risk factors. Individuals without such risk factors lived throughout southwestern Guatemala's five departments. Conclusions The prevalence of CKDnT appears to be much lower in this sample of patients receiving hemodialysis in Southwestern Guatemala than in hospitalized patients in El Salvador. It has yet to be determined whether the prevalence is higher in the general population and in patients on peritoneal dialysis.

摘要

目的 记录危地马拉西南部接受血液透析且患有非传统病因慢性肾脏病(CKDnt)患者的患病率。方法 这项横断面描述性研究对危地马拉社会保障局接受血液透析的患者进行了健康和职业史访谈。通过病历审查获取血液透析开始时的实验室血清、尿液和生命体征数据。根据患者是否患有高血压或肥胖症或两者皆无进行分类。记录有和没有这些传统CKD危险因素患者的比例,并使用多因素逻辑回归分析人口统计学和职业因素与缺乏传统CKD危险因素之间的关联。结果 在危地马拉西南部接受血液透析的242名患者(包括171名非糖尿病患者)中,45名(占总患者的18.6%,占非糖尿病患者的26.3%)缺乏传统的CKD危险因素。虽然农业工作史很常见,但在没有传统危险因素的情况下,只有出行时间超过30分钟和年龄小于50岁与CKD显著相关。没有这些危险因素的个体分布在危地马拉西南部的五个省份。结论 在危地马拉西南部接受血液透析的这组患者中,CKDnT的患病率似乎远低于萨尔瓦多住院患者。普通人群和接受腹膜透析患者的患病率是否更高还有待确定。

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