Rohsenow Damaris J, Martin Rosemarie A, Tidey Jennifer W, Colby Suzanne M, Monti Peter M
Providence Veterans Affairs Medical Center, Providence, RI 02908, USA; Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02912, USA.
Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI 02912, USA.
J Subst Abuse Treat. 2017 Jan;72:72-79. doi: 10.1016/j.jsat.2016.08.012. Epub 2016 Aug 18.
Treatment for substance use disorders (SUD) provides an opportunity to use voucher-based treatment for smoking. Nicotine replacement (NRT) could improve outcomes previously observed with vouchers without NRT.
A randomized controlled trial compared contingent vouchers (CV) for smoking abstinence to noncontingent vouchers (NV), when all received counseling and NRT. Smokers who had not sought smoking treatment (n=340) in residential SUD treatment were provided 14days of vouchers for complete smoking abstinence per exhaled carbon monoxide (CO) after a 5-day smoking reduction period, or vouchers only for breath samples, plus brief advice (four sessions) and 8weeks of NRT.
Within treatment, 20% had complete abstinence with CV, 5% with NV (p<.001), and participants showed 50% of days abstinent in CV compared to 22% in NV (p<.001). Across 1, 3, 6 and 12months after randomization, CV resulted in significantly fewer cigarettes per day (p<.01) and fewer days smoking (p<.01), but with small effects. Point-prevalence abstinence differences across follow-up (e.g., 4% CV, 2% in NV at 6 and 12months) were not significant. No differences in substance use were seen.
Within-treatment effects on abstinence are stronger than in a prior study of the same CV with BA but without NRT, but NRT does not improve abstinence after vouchers end. Implications for voucher-based treatment include investigating effects when combined with stronger smoking medications and using motivational interviewing. Smoking treatment does not harm SUD recovery.
物质使用障碍(SUD)的治疗为采用基于代金券的吸烟治疗提供了契机。尼古丁替代疗法(NRT)可能会改善此前在无NRT的代金券治疗中观察到的结果。
一项随机对照试验将用于戒烟的应急代金券(CV)与非应急代金券(NV)进行了比较,所有受试者均接受咨询和NRT。在住院SUD治疗中未寻求吸烟治疗的吸烟者(n = 340)在经过5天的减烟期后,根据呼出一氧化碳(CO)情况获得14天完全戒烟的代金券,或者仅获得呼吸样本的代金券,外加简短建议(四个疗程)和8周的NRT。
在治疗期间,20%使用CV的受试者实现了完全戒烟,使用NV的为5%(p <.001),且与使用NV的受试者相比,使用CV的受试者有50%的天数戒烟,而使用NV的为22%(p <.001)。在随机分组后的1、3、6和12个月中,CV导致每天吸烟量显著减少(p <.01),吸烟天数减少(p <.01),但效果较小。随访期间的点患病率戒烟差异(例如,6个月和12个月时CV组为4%,NV组为2%)不显著。在物质使用方面未发现差异。
与之前一项对相同CV但无NRT的行为分析研究相比,治疗期间对戒烟的影响更强,但代金券结束后NRT并未改善戒烟情况。基于代金券治疗的意义包括研究与更强效吸烟药物联合使用时的效果以及采用动机性访谈。吸烟治疗不会损害SUD的康复。