Kim Ji Yeon, Kang Eun Kyung, Moon Song Mi, Seo Yiel Hea, Jeong Juhyeon, Cho Hyuni, Yang Dongki, Park Yoon Soo
Division of Infectious Diseases, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Internal Medicine, Gachon University School of Medicine, Gil Medical Center, Incheon, Korea.
Infect Chemother. 2016 Sep;48(3):234-238. doi: 10.3947/ic.2016.48.3.234. Epub 2016 Sep 2.
Actinomyces meyeri is a Gram positive, strict anaerobic bacterium, which was first described by Meyer in 1911. Primary actinomycotic osteomyelitis is rare and primarily affects the cervicofacial region, including mandible. We present an unusual case of osteomyelitis of a long bone combined with myoabscess due to A. meyeri. A 70-year-old man was admitted for pain and pus discharge of the right elbow. Twenty-five days before admission, he had hit his elbow against a table. MRI of the elbow showed a partial tear of the distal triceps tendon and myositis. He underwent open debridement and partial bone resection for the osteomyelitis of the olecranon. Biopsy showed no sulfur granules, but acute and chronic osteomyelitis. The excised tissue grew A. meyeri and Peptoniphilus asaccharolyticus. Intravenous ceftriaxone was administered and switched to oral amoxicillin. Infection of the extremities of actinomycosis often poses diagnostic difficulties, but it should not be neglected even when the characteristic pathologic findings are not present.
迈耶放线菌是一种革兰氏阳性的严格厌氧菌,于1911年由迈耶首次描述。原发性放线菌性骨髓炎较为罕见,主要累及颌面部区域,包括下颌骨。我们报告了一例因迈耶放线菌引起的长骨骨髓炎合并肌脓肿的罕见病例。一名70岁男性因右肘疼痛和流脓入院。入院前25天,他的肘部撞到了桌子。肘部MRI显示肱三头肌远端肌腱部分撕裂和肌炎。他因鹰嘴骨髓炎接受了开放清创和部分骨切除术。活检未发现硫磺颗粒,但有急慢性骨髓炎。切除组织培养出迈耶放线菌和解糖嗜胨菌。给予静脉注射头孢曲松,后改为口服阿莫西林。放线菌病累及四肢时通常会造成诊断困难,但即使没有特征性病理表现也不应忽视。