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[颈面部放线菌病:一例报告]

[Cervicofacial actinomycosis: report of a case].

作者信息

Lee F P, Huang T S, Wang A M

出版信息

Taiwan Yi Xue Hui Za Zhi. 1989 Jul;88(7):744-6.

PMID:2809568
Abstract

Actinomycotic infection involving the head and neck is not commonly diagnosed and is often a diagnostic enigma to the otolaryngologist. The reasons for this are due to the infrequency of this disease itself, the current general lack of familiarity with this disease and the pronounced sensitivity of actinomyces organisms to most of the common antibiotics in current use. The case reported here is fairly typical of cervicofacial actinomycosis. A 26-year-old man suffering from trismus and a noncharacteristic mass over the right parotidomasseteric region for one month after a lower molar tooth was extracted presented at our hospital. There were many yellowish gritty "sulfur granules" found within the pus when surgical drainage was made. Immediate Gram stain examination of these granules showed numerous filamentous Gram-positive bacilli, some of which showed true branching. Bacterial culture grew only an anaerobic organism which was identified as Actinomyces israelii by biochemical tests. This patient improved after further treatment with intensive intravenous penicillin injections for ten days and prolonged oral tetracycline treatment for two months. We suggest that increased alertness of clinicians and microbiologists to the presence of anaerobic organisms as the cause of cervicofacial infections could result in an earlier and more frequent diagnosis of actinomycosis.

摘要

累及头颈部的放线菌感染并不常见,对于耳鼻喉科医生来说常常是一个诊断难题。原因在于这种疾病本身发病率低,目前普遍对其缺乏了解,以及放线菌对当前大多数常用普通抗生素具有显著敏感性。此处报告的病例是颌面部放线菌病的典型病例。一名26岁男性在拔除下颌磨牙后1个月,出现牙关紧闭以及右侧腮腺咬肌区有一非典型肿物,遂来我院就诊。手术引流时在脓液中发现许多淡黄色沙粒样“硫磺颗粒”。对这些颗粒立即进行革兰氏染色检查,显示有大量丝状革兰氏阳性杆菌,其中一些呈现真正的分支。细菌培养仅生长出一种厌氧菌,经生化试验鉴定为以色列放线菌。该患者在进一步接受强化静脉注射青霉素10天及延长口服四环素治疗2个月后病情好转。我们建议临床医生和微生物学家提高对厌氧菌作为颌面部感染病因的警惕性,这可能会使放线菌病得到更早且更频繁的诊断。

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