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肺微石症——一例报告。

Pulmonary microlithiasis - A case report.

作者信息

Mahmood Khalid, Ubaid Muhammad, Mahmood Aamer

机构信息

Dean Faculty of Medicine, Dow University of Health Sciences, Karachi, Pakistan.

Department of Medicine Unit I, Dow University of Health Sciences, Karachi, Pakistan.

出版信息

Respir Med Case Rep. 2016 Aug 31;19:112-4. doi: 10.1016/j.rmcr.2016.08.005. eCollection 2016.

Abstract

Pulmonary alveolar microlithiasis is a rare diffuse lung disease characterized by widespread sand-like intra-alveolar calcifications (calcospherites composed of calcium and phosphorus). Around 800 cases have been reported in the literature to date. We report here a case of a 35 years old female with prolonged h/o of exertional dyspnoea and mild cough. Clinical examination was mostly normal. Her Chest X-Ray revealed bilateral multiple nodular opacities (sand storm appearance). CT Scan chest showed diffuse micronodular calcifications with septal thickening, compatible with alveolar microlithiasis. Pulmonary function tests showed moderately restrictive lung disease. Bronchoscopic alveolar lavage revealed calcospherites in the alveloli and bronchi confirming the diagnosis of pulmonary alveolar microlithiasis.

摘要

肺泡微石症是一种罕见的弥漫性肺部疾病,其特征是肺泡内广泛存在沙样钙化(由钙和磷组成的钙球)。迄今为止,文献报道了约800例病例。我们在此报告一例35岁女性,有长期劳力性呼吸困难和轻度咳嗽病史。临床检查大多正常。她的胸部X线显示双侧多发结节状阴影(沙尘暴样表现)。胸部CT扫描显示弥漫性微小结节钙化伴小叶间隔增厚,符合肺泡微石症表现。肺功能测试显示中度限制性肺病。支气管肺泡灌洗显示肺泡和支气管内有钙球,确诊为肺泡微石症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0d9/5021849/c65700e384b0/gr1.jpg

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