Cao Guangxiang, Zhong Chuanqing, Zong Gongli, Fu Jiafang, Liu Zhong, Zhang Guimin, Qin Ronghuo
Shandong Medicinal Biotechnology Centre, Shandong Academy of Medical Sciences, Jinan, China National Engineering Research Center of Chiral Drugs, Lunan Pharmaceutical Group Corporation, Linyi, China
Shandong Jianzhu University, Jinan, China.
Genome Announc. 2016 Sep 22;4(5):e01020-16. doi: 10.1128/genomeA.01020-16.
Streptomyces clavuligerus strain F613-1 is an industrial strain with high-yield clavulanic acid production. In this study, the complete genome sequence of S. clavuligerus strain F613-1 was determined, including one linear chromosome and one linear plasmid, carrying numerous sets of genes involving in the biosynthesis of clavulanic acid.
棒状链霉菌F613-1菌株是一种高产克拉维酸的工业菌株。在本研究中,测定了棒状链霉菌F613-1菌株的完整基因组序列,包括一条线性染色体和一条线性质粒,其上携带多套参与克拉维酸生物合成的基因。