Kasner O, Feuer W J, Anderson D R
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine.
Can J Ophthalmol. 1989 Aug;24(5):211-5.
We studied optic disc photographs from 137 healthy subjects and 195 subjects with ocular hypertension. The prevalence of peripapillary crescents was lower among hyperopes than among myopes (p less than 0.05). Moreover, the ocular hypertensive subjects had a statistically significant tendency toward a hyperopic median refraction (p less than 0.01). In keeping with this, we observed a lower prevalence rate of crescents in the ocular hypertensive group (35%) than among the healthy subjects (41%). This difference is in the expected direction and magnitude if the absence of a crescent decreases the risk of glaucomatous damage from elevated intraocular pressure, but the number of subjects was too small to obtain statistical significance; however, the evidence is suggestive. Further study, such as in a large population survey or by comparison of two groups with matched genetic heritage, is needed to substantiate the relation between the presence of a crescent and increased risk of glaucomatous damage.
我们研究了137名健康受试者和195名高眼压受试者的视盘照片。远视者中视乳头周围弧形斑的患病率低于近视者（p<0.05）。此外，高眼压受试者有统计学意义的向远视性中值屈光的倾向（p<0.01）。与此一致的是，我们观察到高眼压组弧形斑的患病率（35%）低于健康受试者（41%）。如果没有弧形斑可降低因眼压升高导致青光眼损害的风险，那么这种差异在预期的方向和幅度上，但受试者数量太少，无法获得统计学意义；然而，有一定的提示性证据。需要进一步研究，如进行大规模人群调查或比较两组具有匹配遗传背景的人群，以证实弧形斑的存在与青光眼损害风险增加之间的关系。
