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[慢性肾衰竭甲状旁腺功能亢进症手术治疗的个人经验。I. 继发性甲状旁腺功能亢进症的病因发病机制、术前检查结果、甲状旁腺切除术的指征]

[Personal experience with surgical treatment of hyperparathyroidism in chronic kidney failure. I. Etiopathogenesis of secondary hyperparathyroidism, preoperative findings, indications for parathyroidectomy].

作者信息

Sotorník I, Kocandrle V

出版信息

Cas Lek Cesk. 1989 Jun 9;128(24):742-7.

PMID:2766331
Abstract

The authors give an account of the fundamental relations of the calcium-phosphate metabolism in conjunction with the development of secondary HPT in chronic renal failure. The authors analyzed a group of 20 patients operated on account of secondary and tertiary forms of HPT as regards preoperative findings. The analysis comprised the clinical condition, biochemical, radiological and histological findings pertaining to bone, along with evidence of enlarged parathyroid glands by computed tomography and ultrasonography. The mentioned findings supplemented by some findings from the literature are the sum of indications for PTE. From the practical aspect they are indicators of the affection, of a high total ALP blood level and X-ray evidence of subperiostal absorption.

摘要

作者阐述了钙磷代谢的基本关系以及慢性肾衰竭继发性甲状旁腺功能亢进(HPT)的发展情况。作者分析了一组因继发性和三发性HPT而接受手术的20例患者的术前检查结果。分析内容包括临床状况、与骨骼相关的生化、放射学和组织学检查结果,以及通过计算机断层扫描和超声检查发现的甲状旁腺肿大证据。上述检查结果,再加上文献中的一些检查结果,构成了甲状旁腺切除术(PTE)的指征总和。从实际角度来看,它们是病情的指标,即血液中总碱性磷酸酶(ALP)水平升高以及骨膜下吸收的X线证据。

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