From the Department of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Department of Dermatology, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
QJM. 2016 Dec;109(12):811-812. doi: 10.1093/qjmed/hcw169. Epub 2016 Sep 23.
Gout is a systemic disorder characterized by hyperuricemia and recurrent arthritis, most involvement of ankles, midfoot joint and first metatarsophalangeal joint, with monosodium urate crystals deposition in synovial fluid and other tissues. We present a case of 53-year-old male, who had several nontender, white-yellow papules and plaques over his elbows, knees and arms with chalk-like substances and crust on inflammatory base wax and wane in the past 2 years. Upon histopathology examination of the skin lesions, it reported as intradermal urate tophi and miliarial gout was diagnosed. This case highlights the importance of considering unusual cutaneous tophi in the differential diagnosis of deposition disorders.
痛风是一种以高尿酸血症和反复发作性关节炎为特征的系统性疾病,最常累及踝关节、中足关节和第一跖趾关节,在滑液和其他组织中有单钠尿酸盐晶体沉积。我们报告了一例 53 岁男性患者,他在过去 2 年中肘部、膝盖和手臂上出现了多个无触痛的、黄白色丘疹和斑块,伴有粉笔样物质和炎性基底上的结痂,并且斑块时消时现。皮肤病变的组织病理学检查报告为皮内尿酸盐痛风石,诊断为粟粒性痛风。本例强调了在沉积性疾病的鉴别诊断中考虑不寻常的皮肤痛风石的重要性。