Bowen B D, Bert J L, Gu X, Lund T, Reed R K
Department of Chemical Engineering, University of British Columbia, Vancouver, Canada.
Circ Shock. 1989 Jul;28(3):221-33.
The present work investigates the implications of the predictions of a dynamic mathematical model of microvascular exchange following a nonresuscitated burn injury in a rat (Bert et al.: Circulatory Shock 28:199-219, 1989). Transport coefficients, transmicrovascular pressures, and the resultant fluid and protein fluxes were examined in order to assess their quantitative importance to the dynamic behavior of small (10% body surface area) and large (40% body surface area) burns. Edema accumulation in the injured tissue is dependent not only on events occurring in that tissue but is influenced strongly by interaction with the plasma and the noninjured tissue compartments.
本研究探讨了大鼠非复苏烧伤后微血管交换动态数学模型预测结果的意义（Bert等人：《循环休克》28:199 - 219，1989年）。研究了转运系数、跨微血管压力以及由此产生的液体和蛋白质通量，以评估它们对小面积（10%体表面积）和大面积（40%体表面积）烧伤动态行为的定量重要性。受伤组织中的水肿积聚不仅取决于该组织中发生的事件，还受到与血浆和未受伤组织隔室相互作用的强烈影响。
