Alania Yvette, Chiari Marina D S, Rodrigues Marcela C, Arana-Chavez Victor E, Bressiani Ana Helena A, Vichi Flavio M, Braga Roberto R
Department of Biomaterials and Oral Biology, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil.
Materials Science and Technology Center, Energy and Nuclear Research Institute, Av. Prof. Lineu Prestes 2242, São Paulo, SP 05508-000, Brazil.
Dent Mater. 2016 Dec;32(12):e374-e381. doi: 10.1016/j.dental.2016.09.021. Epub 2016 Sep 21.
To evaluate the strength and ion release of experimental composites containing TEGDMA-functionalized calcium phosphate particles.
Seven composites containing equal parts (in mols) of BisGMA and TEGDMA and 60vol% of fillers were manipulated. Filler phase was constituted by silanized barium glass and 0% (control), 10% or 20% (volume) of dicalcium phosphate dihydrate (DPCD) particles, either non-functionalized or functionalized with two different TEDGMA contents. DCPD particles were synthesized and characterized by X-ray diffraction (XRD), elemental analysis, surface area and dynamic light scattering. Composites were tested for degree of conversion (DC) by near-FTIR. Biaxial flexural strength (BFS) was determined after 24h and 28days in water. Calcium and phosphate release after 7days was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha:5%).
XRD confirmed the crystalline structure corresponding to DCPD. Elemental analysis revealed particles with zero, 14% or 22% TEGDMA, with similar D (around 19μm) and surface areas from 3.5 to 11.4m/g. The presence of DCPD did not reduce DC. After 24h, functionalization (both 14% and 22% TEGDMA) improved composite strength in comparison to non-functionalized DCPD, both at 10% and 20% levels. After 28days, BFS of materials containing 10% functionalized DCPD were statistically similar to the control containing only barium glass. Among composites containing 10% DCPD, particle functionalization with 14% TEGDMA did not jeopardize ion release.
At 10vol%, the use of TEGDMA-functionalized CaP particles improved composite strength in relation to non-functionalized particles, while maintaining similar ion release levels.
评估含有TEGDMA功能化磷酸钙颗粒的实验性复合材料的强度和离子释放情况。
制备了七种复合材料，其含有等摩尔份数的BisGMA和TEGDMA以及60体积%的填料。填料相由硅烷化钡玻璃和0%（对照）、10%或20%（体积）的二水磷酸二钙（DPCD）颗粒组成，DPCD颗粒要么未功能化，要么用两种不同含量的TEGDMA进行功能化。通过X射线衍射（XRD）、元素分析、表面积和动态光散射对DPCD颗粒进行合成和表征。通过近红外傅里叶变换红外光谱（near-FTIR）测试复合材料的转化率（DC）。在水中放置24小时和28天后测定双轴弯曲强度（BFS）。使用电感耦合等离子体发射光谱法（ICP-OES）评估7天后的钙和磷释放情况。数据通过方差分析/ Tukey检验进行分析（α：5%）。
XRD证实了与DPCD相对应的晶体结构。元素分析显示颗粒含有0%、14%或22%的TEGDMA，具有相似的粒径（约19μm）和3.5至11.4m²/g的表面积。DPCD的存在并未降低转化率。24小时后，与未功能化的DPCD相比，功能化（14%和22%的TEGDMA）在10%和20%的含量水平下均提高了复合材料的强度。28天后，含有10%功能化DPCD的材料的BFS在统计学上与仅含有钡玻璃的对照相似。在含有10% DPCD的复合材料中，用14% TEGDMA进行颗粒功能化不会影响离子释放。
在10体积%时，使用TEGDMA功能化的CaP颗粒相对于未功能化的颗粒提高了复合材料的强度，同时保持了相似的离子释放水平。
