Meisler D M, Tomsak R L, Khoury S, Hanson M R, Schwab I R, Ransohoff R M
Cleve Clin J Med. 1989 Jul-Aug;56(5):535-8. doi: 10.3949/ccjm.56.5.535.
Three patients with clinically definite multiple sclerosis and uveitis were studied. The uveitis presented as inflammation of the anterior segment of the eye (iridocyclitis) and was characterized by large keratic precipitates and posterior synechiae, consistent with a granulomatous iridocyclitis. Clinical and laboratory evidence militated against other central nervous system diseases often associated with uveitis including neurosarcoidosis, Behçet's syndrome, Vogt-Koyanagi-Harada disease, neurosyphilis, and tuberculosis. Further attention should be directed to the possibility of granulomatous anterior uveitis in patients with multiple sclerosis.
对3例临床确诊的多发性硬化症合并葡萄膜炎患者进行了研究。葡萄膜炎表现为眼前节炎症（虹膜睫状体炎），其特征为大量角膜后沉着物和虹膜后粘连，符合肉芽肿性虹膜睫状体炎。临床和实验室证据排除了其他常与葡萄膜炎相关的中枢神经系统疾病，包括神经结节病、白塞综合征、伏格特-小柳-原田病、神经梅毒和结核病。对于多发性硬化症患者，应进一步关注肉芽肿性前葡萄膜炎的可能性。
