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腹腔镜根治性前列腺切除术与机器人辅助腹腔镜根治性前列腺切除术功能结局的比较:一项倾向评分匹配比较研究。

Comparison of functional outcomes between laparoscopic radical prostatectomy and robot-assisted laparoscopic radical prostatectomy: a propensity score-matched comparison study.

作者信息

Ku Ja Yoon, Lee Chan Ho, Lee Jeong Zoo, Ha Hong Koo

机构信息

Department of Urology, Pusan National University School of Medicine and, Busan, South Korea.

Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.

出版信息

Asia Pac J Clin Oncol. 2017 Jun;13(3):212-218. doi: 10.1111/ajco.12595. Epub 2016 Sep 26.

Abstract

AIM

To compare the functional outcomes after laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic radical prostatectomy (RARP).

METHODS

Between September 2008 and January 2016, 712 patients underwent radical prostatectomy (RP; 614 LRP and 98 RARP). Recovery of incontinence was evaluated through a 24-h pad test. Urinary and erectile function was evaluated using the International Prostate Symptom Score (IPSS) and the International Index of Erectile Function-5. Follow-up interval was 1, 3, 6 and 12 months after the surgery. The propensity score matching was used to balance the preoperative characteristics.

RESULTS

The recovery of incontinence was similar to the two groups at 6 and 12 months after the surgery. However, patients underwent RARP restored the continence sooner than those in the LRP group in 1 and 3 months after the surgery (P < 0.001 and 0.001). For the multivariable analysis, the type of RP procedure was a uniquely meaningful contributing factor (P = 0.001, HR = 1.925; 95% CI, 1.299-2.851). In the case of urinary function, the RARP groups showed a better IPSS score than LRP groups at the 1-, 3- and 6-month visits, respectively (P = 0.008, 0.026, 0.001), and the RARP groups early improved compared with LRP groups at the 3-month visit in the case of erectile function (P = 0.018).

CONCLUSION

The RARP tended toward getting back the urinary continence earlier than the LRP. In addition, urinary and erectile function recovered more quickly in the RARP group than in the LRP group.

摘要

目的

比较腹腔镜根治性前列腺切除术(LRP)和机器人辅助腹腔镜根治性前列腺切除术(RARP)后的功能结局。

方法

2008年9月至2016年1月期间,712例患者接受了根治性前列腺切除术(RP;614例行LRP,98例行RARP)。通过24小时尿垫试验评估尿失禁的恢复情况。使用国际前列腺症状评分(IPSS)和国际勃起功能指数-5评估排尿和勃起功能。术后随访时间为1、3、6和12个月。采用倾向评分匹配法平衡术前特征。

结果

术后6个月和12个月时,两组尿失禁的恢复情况相似。然而,RARP组患者在术后1个月和3个月时比LRP组患者更早恢复控尿(P<0.001和0.001)。多变量分析显示,RP手术类型是唯一有意义的影响因素(P=0.001,HR=1.925;95%CI,1.299-2.851)。在排尿功能方面,RARP组在术后1个月、3个月和6个月时的IPSS评分分别优于LRP组(P=0.008、0.026、0.001);在勃起功能方面,RARP组在术后3个月时比LRP组更早改善(P=0.018)。

结论

RARP比LRP更倾向于更早恢复尿控。此外,RARP组的排尿和勃起功能恢复比LRP组更快。

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