Blackburn Lisa M, Bauchmire Nicole, Bender Sarah, Tomlinson-Pinkham Kelly, Roberts Scott, Rosan Sherry
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, OH.
Ohio State University Comprehensive Cancer Center.
Clin J Oncol Nurs. 2016 Oct 1;20(5):523-7. doi: 10.1188/16.CJON.523-527.
Acute promyelocytic leukemia (APL), once the most lethal form of adult acute leukemia, has become the most curable. The goal of early and well-managed treatment induction is to reduce the malignant burden of promyelocytes to below the cytologically detectable level.
Oncology nurses who care for patients with APL need to be acutely aware of the basic differences in this disease from other forms of leukemia, including the two main complications for the newly diagnosed patient.
This article will briefly review APL and its associated presenting symptoms, prognosis, treatment, and complications.
These complications require immediate activation of expert staff and resources to protect critically ill patients with APL from associated morbidity and mortality.
急性早幼粒细胞白血病（APL）曾是成人急性白血病中最致命的类型，如今已成为最可治愈的类型。早期且管理良好的诱导治疗目标是将早幼粒细胞的恶性负担降低至细胞学可检测水平以下。
护理APL患者的肿瘤护士需要敏锐地意识到这种疾病与其他形式白血病的基本差异，包括新诊断患者的两种主要并发症。
本文将简要回顾APL及其相关的症状表现、预后、治疗和并发症。
这些并发症需要立即启动专家团队和资源，以保护重症APL患者免受相关发病和死亡风险。
