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本文引用的文献

1
Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients.在接受蒽环类药物治疗的患者中,通过外周静脉注射福沙匹坦可引起高频且增强的注射部位反应。
J Cancer. 2014 Apr 24;5(5):390-7. doi: 10.7150/jca.7706. eCollection 2014.
2
Incidence of infusion-site reactions associated with peripheral intravenous administration of fosaprepitant.福沙匹坦经外周静脉给药相关输液部位反应的发生率。
Support Care Cancer. 2014 Jun;22(6):1461-6. doi: 10.1007/s00520-013-2106-y. Epub 2014 Jan 9.
3
Fosaprepitant-induced phlebitis: a focus on patients receiving doxorubicin/cyclophosphamide therapy.福沙匹坦引起的静脉炎:聚焦于接受多柔比星/环磷酰胺治疗的患者。
Support Care Cancer. 2014 May;22(5):1313-7. doi: 10.1007/s00520-013-2089-8. Epub 2014 Jan 9.
4
Infusion phlebitis assessment measures: a systematic review.静脉输液性静脉炎评估措施:一项系统评价
J Eval Clin Pract. 2014 Apr;20(2):191-202. doi: 10.1111/jep.12107. Epub 2014 Jan 8.
5
Pharmacokinetic evaluation of fosaprepitant dimeglumine.福沙匹坦二甲葡胺的药代动力学评价。
Expert Opin Drug Metab Toxicol. 2010 Oct;6(10):1277-86. doi: 10.1517/17425255.2010.513970.
6
A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting.NK1拮抗剂阿瑞匹坦与昂丹司琼预防术后恶心和呕吐的随机双盲对照研究。
Anesth Analg. 2007 May;104(5):1082-9, tables of contents. doi: 10.1213/01.ane.0000263277.35140.a3.

接受致吐方案治疗的患者使用磷丙泊酚的获益与风险

Benefits and Risks of Fosaprepitant in Patients Receiving Emetogenic Regimens.

作者信息

Pritchett Wendy, Kinsley Karen

机构信息

Memorial Sloan Kettering Cancer Center.

出版信息

Clin J Oncol Nurs. 2016 Oct 1;20(5):555-6. doi: 10.1188/16.CJON.555-556.

DOI:10.1188/16.CJON.555-556
PMID:27668376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5510647/
Abstract

Fosaprepitant dimeglumine (Emend IV®) is an IV antiemetic that may be beneficial to patients receiving highly emetogenic regimens. Aprepitant (Emend®) is an oral medication that is administered for three consecutive days, whereas fosaprepitant is a single-dose IV medication that is administered on the day of chemotherapy for 20-30 minutes (depending on the IV access type). Fosaprepitant may be useful, yet it can also present a risk for hypersensitivity reactions and phlebitis. Oncology nurses must be aware of the signs and symptoms of these potential adverse events to properly care for their patients.

摘要

磷丙泊酚二钠(Emend IV®)是一种静脉用止吐药,可能对接受高致吐性化疗方案的患者有益。阿瑞匹坦(Emend®)是一种口服药物,需连续服用三天,而磷丙泊酚二钠是一种单剂量静脉用药,在化疗当天给药,持续20 - 30分钟(取决于静脉通路类型)。磷丙泊酚二钠可能有用,但也可能有过敏反应和静脉炎的风险。肿瘤专科护士必须了解这些潜在不良事件的体征和症状,以便妥善护理患者。