Eigenmann A K, Kuhn M
Medizinische Klinik, Kantonsspital Chur.
Dtsch Med Wochenschr. 1989 Sep 1;114(35):1320-3. doi: 10.1055/s-2008-1066760.
Three weeks after starting treatment with the antidepressant trimipramine a 55-year-old man developed increasing cough, fatigue and lack of appetite. The blood count revealed marked eosinophilia (15%) and the chest X-ray showed bilateral pulmonary infiltrates. Later a left spontaneous pneumothorax occurred. When trimipramine was discontinued (as the suspected cause of the described changes) the symptoms quickly subsided and the infiltrate as well as the eosinophilia quickly disappeared.
在开始使用抗抑郁药三甲丙咪嗪治疗三周后，一名55岁男性出现咳嗽加重、疲劳和食欲不振。血细胞计数显示明显的嗜酸性粒细胞增多（15%），胸部X线显示双侧肺部浸润。后来发生了左侧自发性气胸。当停用三甲丙咪嗪（作为上述变化的疑似原因）后，症状迅速缓解，浸润以及嗜酸性粒细胞增多也很快消失。
