Celano Christopher M, Daunis Daniel J, Lokko Hermioni N, Campbell Kirsti A, Huffman Jeff C
Harvard Medical School, Boston, MA, USA.
Department of Psychiatry, Massachusetts General Hospital, Blake 11, 55 Fruit Street, Boston, MA, 02114, USA.
Curr Psychiatry Rep. 2016 Nov;18(11):101. doi: 10.1007/s11920-016-0739-5.
Anxiety and its associated disorders are common in patients with cardiovascular disease and may significantly influence cardiac health. Anxiety disorders are associated with the onset and progression of cardiac disease, and in many instances have been linked to adverse cardiovascular outcomes, including mortality. Both physiologic (autonomic dysfunction, inflammation, endothelial dysfunction, changes in platelet aggregation) and health behavior mechanisms may help to explain the relationships between anxiety disorders and cardiovascular disease. Given the associations between anxiety disorders and poor cardiac health, the timely and accurate identification and treatment of these conditions is of the utmost importance. Fortunately, pharmacologic and psychotherapeutic interventions for the management of anxiety disorders are generally safe and effective. Further study is needed to determine whether interventions to treat anxiety disorders ultimately impact both psychiatric and cardiovascular health.
焦虑及其相关障碍在心血管疾病患者中很常见,可能会显著影响心脏健康。焦虑症与心脏病的发生和发展有关,在许多情况下还与不良心血管结局(包括死亡率)相关。生理机制(自主神经功能障碍、炎症、内皮功能障碍、血小板聚集变化)和健康行为机制都有助于解释焦虑症与心血管疾病之间的关系。鉴于焦虑症与心脏健康不佳之间的关联,及时、准确地识别和治疗这些病症至关重要。幸运的是,用于管理焦虑症的药物和心理治疗干预通常是安全有效的。需要进一步研究以确定治疗焦虑症的干预措施是否最终会对精神和心血管健康产生影响。