Yu Jeong Il, Park Hee Chul, Ahn Yong Chan, Gao Xian-Shu, Wang Jun-Jie, Zeng Zhao-Chong, Ito Yoshinori, Ohno Tatsuya, Nishimura Yasumasa
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea.
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, #50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea
J Radiat Res. 2017 Jan;58(1):155-163. doi: 10.1093/jrr/rrw089. Epub 2016 Sep 26.
This online survey of practising radiation oncologists from Korea, China and Japan was conducted to investigate the current practices in radiotherapy (RT) for spine metastasis and to compare these practices across the three countries. The questionnaire included nine general information questions and two clinical scenarios (representing 'typical' and 'good' prognosis spine metastasis), with seven questions for each scenario. An anonymous web-based survey using Google Docs® was undertaken from 2 September 2014 to 9 April 2015. A total of 54 Korean, 107 Chinese and 104 Japanese radiation oncologists participated in the study. The first scenario involved a typical case of spine metastasis (~25% expected 1-year survival rate), and the preferred fractionation scheme was 10 fractions of 3 Gy, though the pattern was slightly different in each country. The second scenario involved a good prognosis case (>50% expected 1-year survival rate), and 10 fractions of 3 Gy was the preferred practice in all three countries (however, use of a larger fraction dose with a smaller fraction number was more common in Korea). A more conformal RT technique was more prominent in China and Korea, especially for patients with a good prognosis. Avoidance of reirradiation was notable in China. In summary, a preference for multiple fractionation in RT for spine metastasis was observed in the majority of Korean, Chinese and Japanese radiation oncologists, although there were slight differences in practice preferences, especially for patients with a favorable prognosis.
这项针对韩国、中国和日本执业放射肿瘤学家的在线调查旨在研究脊柱转移瘤放射治疗（RT）的当前实践情况，并比较这三个国家的这些实践。问卷包括九个一般信息问题和两个临床病例（分别代表“典型”和“预后良好”的脊柱转移瘤），每个病例有七个问题。2014年9月2日至2015年4月9日期间，通过谷歌文档®进行了一项基于网络的匿名调查。共有54名韩国、107名中国和104名日本放射肿瘤学家参与了该研究。第一个病例是典型的脊柱转移瘤（预计1年生存率约为25%），尽管各国的模式略有不同，但首选的分割方案是10次，每次3 Gy。第二个病例是预后良好的病例（预计1年生存率>50%），在所有三个国家，首选的做法都是10次，每次3 Gy（然而，在韩国，使用较大分割剂量和较少分割次数更为常见）。在中国和韩国，更适形的RT技术更为突出，尤其是对于预后良好的患者。在中国，避免再次放疗的情况较为明显。总之，大多数韩国、中国和日本的放射肿瘤学家在脊柱转移瘤的RT中倾向于多分次，尽管在实践偏好上存在细微差异，尤其是对于预后良好的患者。
